Dr. Pichamol Jirapinyo, MD, MPH

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Brigham and Women's Hospital

Studies Obesity
Studies Diabetes
4 reported clinical trials
5 drugs studied

Affiliated Hospitals

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Brigham And Women's Hospital

Clinical Trials Pichamol Jirapinyo, MD, MPH is currently running

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ESG + GLP-1RA

for Obesity and Liver Fibrosis

Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease globally. While weight loss through lifestyle modification is the standard treatment, most patients regain weight limiting ultimate improvement in liver disease. On the other end of the spectrum, bariatric surgery has shown promise in the treatment of MASLD/metabolic dysfunction-associated steatohepatitis (MASH) due to its efficacy in inducing weight loss. Nevertheless, its adoption has been hindered by the perceived invasiveness of surgery. Over the past decade, endoscopic sleeve gastroplasty (ESG) has gained recognition as a promising minimally-invasive approach to weight loss. The procedure involves utilizing a Food and Drug Administration (FDA)-authorized endoscopic suturing device to reduce the gastric volume by 70%. Studies reveal that ESG is associated with approximately 18.2% weight loss at one year after the procedure, with sustained results for at least 10 years. Nevertheless, the effect of ESG on MASH remains unknown. In this study, the investigators will compare ESG + lifestyle modification versus lifestyle modification alone in treating histologic MASH. The study will randomize patients to one of two different treatment options: ESG + lifestyle modification or lifestyle modification alone.
Recruiting1 award N/A8 criteria
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RESET Liner

for Type-2 Diabetes and Obesity

This trial is testing the RESET System, a device placed in the stomach, to help people with Type 2 Diabetes and Obesity who haven't controlled their blood sugar well with current medications. The device works by reducing food absorption, aiding in better blood sugar control and weight loss. The RESET System has been shown to help with weight loss and better blood sugar control in patients with type 2 diabetes.
Recruiting0 awards N/A3 criteria

More about Pichamol Jirapinyo, MD, MPH

Clinical Trial Related1 year of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Pichamol Jirapinyo, MD, MPH has experience with
  • Endoscopic Sleeve Gastroplasty (ESG)
  • GLP1-RA
  • EndoBarrier Liner
  • Sham
  • P-ESG

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