Dr. Renee Stapleton, MD, PhD
Claim this profileUniversity of Vermont
Studies Acute Respiratory Failure
Studies Respiratory Insufficiency
4 reported clinical trials
4 drugs studied
Affiliated Hospitals
Clinical Trials Renee Stapleton, MD, PhD is currently running
Ganciclovir
for Acute Respiratory Failure
This is a phase 3 study designed to evaluate whether the administration of ganciclovir increases ventilator-free days in immunocompetent patients with sepsis associated acute respiratory failure. Our hypothesis is that IV ganciclovir administered early in critical illness will effectively suppress CMV reactivation in CMV seropositive adults with sepsis-associated acute respiratory failure thereby leading to improved clinical outcomes
Recruiting1 award Phase 37 criteria
NMES
for COPD and Pneumonia
In older adults hospitalized for acute medical conditions, immobility, clinical treatments, and the illness itself contribute to physical deconditioning and delirium, hospital-acquired impairments that increase risk for long-term physical and mental disability, other morbidities, and death. In patients with acute respiratory failure, hospital-acquired functional impairments persist long after hospitalization, due to limited use to rehabilitative interventions in the inpatient or post-acute settings. Exercise and early mobilization interventions are safe and improve physical and cognitive impairments, but there are critical barriers to their widespread implementation in acute care and home settings, including mobility limitations, reduced cardiopulmonary reserve, limited staff, and costs. Thus, there is an unmet need to develop interventions that can be utilized in both the inpatient and home environments to improve functional recovery in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and community-acquired pneumonia (CAP). This study addresses this clinical need and these barriers and will provide important feasibility and acceptability data regarding the utility of neuromuscular electrical stimulation (NMES) administered to lower extremity musculature across inpatient and post-discharge settings to improve functional and cognitive recovery in older adults hospitalized for AECOPD/CAP. Initial NMES sessions will begin during participants' stay at UVM Medical Center and will continue at home after hospital discharge. Study participants will be issued a portable NMES device to take home and instructed on its use. They will receive guidance and oversight on the use of the NMES device and will be asked to perform NMES treatments 6 days per week for 60 minutes per day for 6 weeks. Data will be collected via activity monitor, participant questionnaires and clinical assessments including strength testing and 6-minute-walk-test.
Recruiting1 award N/A3 criteria
More about Renee Stapleton, MD, PhD
Clinical Trial Related3 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Renee Stapleton, MD, PhD has experience with
- Ganciclovir
- Exersides
- Covid-19+ Observational
- NMES
Breakdown of trials Renee Stapleton, MD, PhD has run
Acute Respiratory Failure
Respiratory Insufficiency
Respiratory Distress Syndrome
Encephalopathy
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Renee Stapleton, MD, PhD specialize in?
Renee Stapleton, MD, PhD focuses on Acute Respiratory Failure and Respiratory Insufficiency. In particular, much of their work with Acute Respiratory Failure has involved treating patients, or patients who are undergoing treatment.
Is Renee Stapleton, MD, PhD currently recruiting for clinical trials?
Yes, Renee Stapleton, MD, PhD is currently recruiting for 2 clinical trials in Burlington Vermont. If you're interested in participating, you should apply.
Are there any treatments that Renee Stapleton, MD, PhD has studied deeply?
Yes, Renee Stapleton, MD, PhD has studied treatments such as Ganciclovir, Exersides, Covid-19+ observational.
What is the best way to schedule an appointment with Renee Stapleton, MD, PhD?
Apply for one of the trials that Renee Stapleton, MD, PhD is conducting.
What is the office address of Renee Stapleton, MD, PhD?
The office of Renee Stapleton, MD, PhD is located at: University of Vermont, Burlington, Vermont 05405 United States. This is the address for their practice at the University of Vermont.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.