Dr. Ronald L. Paquette
Claim this profileCedars-Sinai Medical Center
Affiliated Hospitals
Cedars-Sinai Medical Center
Clinical Trials Ronald L. Paquette is currently running
Cyclophosphamide After Stem Cell Transplant
for Blood Cancer
The purpose of this phase 1 study is to determine the optimal dose of the immune suppressive drug, cyclophosphamide, following standard allogeneic stem cell transplant in patients aged \>/= 65 years with hematologic malignancies.
Recruiting
1 award
Phase 1
Stem Cell + CAR T-Cell Therapy
for Blood Cancers
The study is designed to examine the feasibility and safety of collecting autologous hematopoietic stem cells (HSCs) to be combined with CAR T-cell therapy for patients with relapsed/refractory (r/r) hematological disease. The study will evaluate feasibility of collecting the target dose of HSCs from at least 50% of enrolled patients. The study will assess safety based on incidence and severity of cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) in the first 60 days post CAR T dosing, and also through the collection of adverse events (AEs) and serious adverse events (SAEs) as well as the durability of response after treatment with HSCs with CAR T. The study follows an open-label, single-center and single non-randomized cohort design. 20 subjects with r/r hematological malignancies will be enrolled and treated to evaluate the feasibility and preliminary safety of collecting autologous HSCs and combining them with CAR T-cell therapy.
Recruiting
1 award
Phase 1
11 criteria
More about Ronald L. Paquette
Clinical Trial Related
2 years of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Ronald L. Paquette has experience with
- Cyclophosphamide
- Daratumumab/rHuPH20
- Lenalidomide
- Blinatumomab
- Haplo-Mismatched Cell Therapy (HMCT)
- Autologous Hematopoietic Stem Cells With Chimeric Antigen Receptor (CAR) T-Cell Therapy
Breakdown of trials Ronald L. Paquette has run
Cancer
Blood Cancers
Multiple Myeloma
Acute Lymphoblastic Leukemia
Burkitt Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Ronald L. Paquette specialize in?
Ronald L. Paquette focuses on Cancer and Blood Cancers. In particular, much of their work with Cancer has involved treating patients, or patients who are undergoing treatment.
Is Ronald L. Paquette currently recruiting for clinical trials?
Yes, Ronald L. Paquette is currently recruiting for 2 clinical trials in Los Angeles California. If you're interested in participating, you should apply.
Are there any treatments that Ronald L. Paquette has studied deeply?
Yes, Ronald L. Paquette has studied treatments such as Cyclophosphamide, Daratumumab/rHuPH20, Lenalidomide.
What is the best way to schedule an appointment with Ronald L. Paquette?
Apply for one of the trials that Ronald L. Paquette is conducting.
What is the office address of Ronald L. Paquette?
The office of Ronald L. Paquette is located at: Cedars-Sinai Medical Center, Los Angeles, California 90048 United States. This is the address for their practice at the Cedars-Sinai Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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