Sarah K. Tasian, MD | Children's ...

Dr. Sarah Tasian, MD

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Children's Hospital of Philadelphia

Studies Acute Myeloid Leukemia
Studies Acute Myelogenous Leukemia
5 reported clinical trials
9 drugs studied

Affiliated Hospitals

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Children's Hospital Of Philadelphia

Clinical Trials Sarah Tasian, MD is currently running

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Diagnostic Testing

for Pediatric Leukemia

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.
Recruiting1 award Phase 1 & 211 criteria
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Imetelstat + Chemotherapy

for Acute Myeloid Leukemia

This phase I trial tests the safety, side effects, and best dose of imetelstat in combination with fludarabine and cytarabine in treating patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) or juvenile myelomonocytic leukemia (JMML) that has not responded to previous treatment (refractory) or that has come back after a period of improvement (recurrent). Imetelstat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as fludarabine and cytarabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving imetelstat in combination with fludarabine and cytarabine may work better in treating patients with refractory or recurrent AML, MDS, and JMML.
Recruiting1 award Phase 14 criteria

More about Sarah Tasian, MD

Clinical Trial Related3 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Sarah Tasian, MD has experience with
  • Cytarabine
  • Fludarabine
  • Matched Targeted Therapy
  • Methotrexate
  • Selinexor
  • Venetoclax

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