Dr. Savita Dandapani, MD
Claim this profileCity of Hope Medical Center
Studies Cancer
Studies Lymphoma
8 reported clinical trials
19 drugs studied
Affiliated Hospitals
Clinical Trials Savita Dandapani, MD is currently running
Radiation Therapy + CAR T-Cell Therapy
for Lymphoma
This early phase I clinical trial evaluates bridging radiation therapy given before chimeric antigen receptor (CAR) T-cell infusion to treat large B-cell lymphoma (LBCL) that has come back (relapsed) or has not responded to previous treatment (refractory). Patients with relapsed or refractory disease have historically poor prognosis. CAR T-cell therapy is a type of treatment in which a patient's T-cells (a type of immune system cell) are changed in the laboratory so they will attack cancer cells. T-cells are taken from a patient's blood (leukapheresis). Then the gene for a special receptor that binds to a certain protein on the patient's cancer cells is added to the T-cells in the laboratory. The special receptor is called a chimeric antigen receptor (CAR). Large numbers of the CAR T-cells are grown in the laboratory and given to the patient by infusion for treatment of certain cancers. While the outcomes from CAR T-cell therapy appear favorable, in the time between leukapheresis and CAR T-cell infusion many patients have symptomatic or life-threatening disease which often requires bridging therapy. Bridging therapy aims to slow disease progression and control symptoms during this critical period prior to CAR T-cell infusion. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells. Giving bridging radiation therapy to patients with relapsed or refractory LBCL prior to CAR T-cell infusion may improve treatment outcomes with minimal toxicity.
Recruiting1 award Phase < 1
Stereotactic Body Radiation Therapy
for Cancer
This trial uses radiation therapy and a special PET scan to help lymphoma and metastatic solid tumor patients. The radiation attracts immune cells to fight the cancer, and the scan checks if these cells are working properly.
Recruiting1 award Phase 1
More about Savita Dandapani, MD
Clinical Trial Related6 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Savita Dandapani, MD has experience with
- Stereotactic Body Radiation Therapy
- Chimeric Antigen Receptor T-Cell Therapy
- External Beam Radiation Therapy
- Goserelin Acetate
- Leuprolide Acetate
- Radium Ra 223 Dichloride
Breakdown of trials Savita Dandapani, MD has run
Cancer
Lymphoma
Prostate Adenocarcinoma
Prostate Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Savita Dandapani, MD specialize in?
Savita Dandapani, MD focuses on Cancer and Lymphoma. In particular, much of their work with Cancer has involved Stage IV patients, or patients who are undergoing treatment.
Is Savita Dandapani, MD currently recruiting for clinical trials?
Yes, Savita Dandapani, MD is currently recruiting for 4 clinical trials in Duarte California. If you're interested in participating, you should apply.
Are there any treatments that Savita Dandapani, MD has studied deeply?
Yes, Savita Dandapani, MD has studied treatments such as Stereotactic Body Radiation Therapy, Chimeric Antigen Receptor T-Cell Therapy, External Beam Radiation Therapy.
What is the best way to schedule an appointment with Savita Dandapani, MD?
Apply for one of the trials that Savita Dandapani, MD is conducting.
What is the office address of Savita Dandapani, MD?
The office of Savita Dandapani, MD is located at: City of Hope Medical Center, Duarte, California 91010 United States. This is the address for their practice at the City of Hope Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.