Dr. Seema A. Bhat

Claim this profile

Ohio State University Comprehensive Cancer Center

Studies Chronic Lymphocytic Leukemia
Studies Lymphoma
2 reported clinical trials
4 drugs studied

Area of expertise

1

Chronic Lymphocytic Leukemia

Seema A. Bhat has run 2 trials for Chronic Lymphocytic Leukemia. Some of their research focus areas include:

13q positive
13q negative
12 positive
2

Lymphoma

Seema A. Bhat has run 2 trials for Lymphoma. Some of their research focus areas include:

13q positive
13q negative
12 positive

Affiliated Hospitals

Image of trial facility.

Ohio State University Comprehensive Cancer Center

Clinical Trials Seema A. Bhat is currently running

Image of trial facility.

Pneumococcal Vaccination

for Chronic Lymphocytic Leukemia

This phase II trial compares the effect of initial vaccination (PCV20 followed by PSV23) with yearly vaccinations of PSV23 to the standard 5 year vaccination in patients with chronic lymphocytic leukemia. At present chronic lymphocytic leukemia patients are poorly protected by anti-pneumococcal vaccination. Current vaccination schedule for chronic lymphocytic leukemia patients is based on general recommendations in immunocompromised patients (initial vaccination with PCV13 followed by one dose of PSV23 after an interval of two months, followed by revaccination at 5 years). Giving patients frequent immunization as compared to 5 year immunization may result in higher protective titers in patients.

Recruiting

2 awards

Phase 2

Image of trial facility.

Venetoclax + Obinutuzumab

for Leukemia

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Immunotherapy with monoclonal antibodies, such as obinutuzumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Starting treatment with the venetoclax and obinutuzumab early (before patients have symptoms) may have better outcomes for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma compared to starting treatment with the venetoclax and obinutuzumab after patients show symptoms.

Recruiting

2 awards

Phase 3

1 criteria

More about Seema A. Bhat

Clinical Trial Related

2 years of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Seema A. Bhat has experience with

  • Pneumococcal 13-valent Conjugate Vaccine
  • Pneumococcal Polyvalent Vaccine
  • Obinutuzumab
  • Venetoclax

Other Doctors you might be interested in

Frequently asked questions

Do I need insurance to participate in a trial?

What does Seema A. Bhat specialize in?

Is Seema A. Bhat currently recruiting for clinical trials?

Are there any treatments that Seema A. Bhat has studied deeply?

What is the best way to schedule an appointment with Seema A. Bhat?

What is the office address of Seema A. Bhat?

Is there any support for travel costs?