Dr. Shanu Modi, MD
Claim this profileMemorial Sloan Kettering Cancer Center
Studies Breast Cancer
Studies Breast cancer
8 reported clinical trials
16 drugs studied
Area of expertise
1Breast Cancer
Stage IV
HER2 positive
Stage III
2Breast Cancer
HER2 positive
Stage III
Stage II
Affiliated Hospitals
Clinical Trials Shanu Modi, MD is currently running
Disitamab Vedotin + Tucatinib
for Breast Cancer
This clinical trial is studying solid tumor cancers. A solid tumor is one that starts in part of your body like your lungs or liver instead of your blood. Once they've grown bigger in one spot or spread to other parts of the body, they're harder to treat. This is called advanced or metastatic cancer. Participants in this study must have breast cancer or gastric cancer. Participants must have tumors that have HER2 on them. This allows the cancer to grow more quickly or spread faster. There are few treatment options for patients with advanced or metastatic solid tumors that express HER2. This clinical trial uses an experimental drug called disitamab vedotin (DV). Disitamab vedotin is a type of antibody drug conjugate or ADC. ADCs are designed to stick to cancer cells and kill them. This clinical trial uses a drug called tucatinib, which has been approved to treat cancer in the United States and some other countries. This drug is sold under the brand name TUKYSA®. This study will test how safe and how well DV, with or without tucatinib, is for participants with solid tumors. This study will also test what side effects happen when participants take these drugs. A side effect is anything a drug does to the body besides treating the disease.
Recruiting1 award Phase 1 & 26 criteria
Chemotherapy Reduction After Surgery
for Breast Cancer
This trial studies how well paclitaxel, trastuzumab, and pertuzumab work in eliminating further chemotherapy after surgery in patients with HER2-positive stage II-IIIa breast cancer who have no cancer remaining at surgery (either in the breast or underarm lymph nodes) after pre-operative chemotherapy and HER2-targeted therapy. Drugs used in chemotherapy, such as paclitaxel, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Trastuzumab and pertuzumab are both a form of "targeted therapy" because they work by attaching themselves to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When these drugs attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Giving paclitaxel, trastuzumab, and pertuzumab may enable fewer chemotherapy drugs to be given without compromising patient outcomes compared to the usual treatment.
Recruiting1 award Phase 227 criteria
More about Shanu Modi, MD
Clinical Trial Related11 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Shanu Modi, MD has experience with
- Trastuzumab
- Tucatinib
- AP1903
- Cyclophosphamide
- Mesothelin-targeted T Cells
- Bicalutamide
Breakdown of trials Shanu Modi, MD has run
Breast Cancer
Breast cancer
Uterine Tumors
Stomach Tumors
Gastric Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Shanu Modi, MD specialize in?
Shanu Modi, MD focuses on Breast Cancer and Breast cancer. In particular, much of their work with Breast Cancer has involved Stage IV patients, or patients who are HER2 positive.
Is Shanu Modi, MD currently recruiting for clinical trials?
Yes, Shanu Modi, MD is currently recruiting for 2 clinical trials in New York New York. If you're interested in participating, you should apply.
Are there any treatments that Shanu Modi, MD has studied deeply?
Yes, Shanu Modi, MD has studied treatments such as Trastuzumab, Tucatinib, AP1903.
What is the best way to schedule an appointment with Shanu Modi, MD?
Apply for one of the trials that Shanu Modi, MD is conducting.
What is the office address of Shanu Modi, MD?
The office of Shanu Modi, MD is located at: Memorial Sloan Kettering Cancer Center, New York, New York 10065 United States. This is the address for their practice at the Memorial Sloan Kettering Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.