Dr. Sharmila Anandasabapathy, MD

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Studies Cancer
Studies Skin Cancer
1 reported clinical trial
2 drugs studied

Clinical Trials Sharmila Anandasabapathy, MD is currently running

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Optical Biopsy Technology

for Esophageal Cancer

In a previous clinical trial in China and the United States (US), the investigators developed and validated a mobile, high-resolution microendoscope (mHRME) for screening and surveillance of esophageal squamous cell neoplasia (ESCN). The trial revealed higher specificity for qualitative (visual) interpretation by experts but not the novice and in the surveillance arm (100% vs. 19%, p \<0.05). In the screening arm, diagnostic yield (neoplastic biopsies/total biopsies) increased 3.6 times (8 to 29%); 16% of patients were correctly spared any biopsy, and 18% had a change in clinical plan. In a pilot study in Brazil, the investigators tested a software-assisted mHRME with deep-learning software algorithms to aid in the detection of neoplastic images and determine the performance, efficiency, and impact of the AI-mHRME when to Lugol's chromoendoscopy (LCE) alone and when using AI-mHRME with LCE. In this clinical trial, the investigators will build on the Brazil pilot trial data to optimize an artificial intelligence (AI) mHRME and evaluate its clinical impact and implementation potential in ethnically and socioeconomically diverse populations in the US and Brazil.

Recruiting

1 award

Phase 2

1 criteria

More about Sharmila Anandasabapathy, MD

Clinical Trial Related

1 year of experience running clinical trials · Led 1 trial as a Principal Investigator · 1 Active Clinical Trial

Treatments Sharmila Anandasabapathy, MD has experience with

  • Artificial Intelligence Mobile High-Resolution Microendoscope
  • Proflavine Hemisulfate

Breakdown of trials Sharmila Anandasabapathy, MD has run

Cancer

Skin Cancer

Precancerous lesions

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