Dr. Stacy Cooper, MD, Oncology ...

Dr. Stacy L. Cooper

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Johns Hopkins University/Sidney Kimmel Cancer Center

Studies Acute Lymphoblastic Leukemia
Studies Burkitt Lymphoma
8 reported clinical trials
15 drugs studied

Area of expertise

1Acute Lymphoblastic Leukemia
Stacy L. Cooper has run 4 trials for Acute Lymphoblastic Leukemia. Some of their research focus areas include:
Stage IV
CRLF2 positive
CRLF2 negative
2Burkitt Lymphoma
Stacy L. Cooper has run 3 trials for Burkitt Lymphoma. Some of their research focus areas include:
Stage IV
CD19 positive
CRLF2 positive

Affiliated Hospitals

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Johns Hopkins University/Sidney Kimmel Cancer Center
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The Johns Hopkins Hospital JHH

Clinical Trials Stacy L. Cooper is currently running

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Levocarnitine

for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma

This phase III trial compares the effect of adding levocarnitine to standard chemotherapy versus (vs.) standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.
Recruiting2 awards Phase 3
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Diagnostic Testing

for Pediatric Leukemia

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.
Recruiting1 award Phase 1 & 211 criteria

More about Stacy L. Cooper

Clinical Trial Related8 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 5 Active Clinical Trials
Treatments Stacy L. Cooper has experience with
  • Nivolumab
  • Brentuximab Vedotin
  • Cyclophosphamide
  • Relatlimab
  • Bendamustine
  • Blinatumomab

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