Dr. Stanley Chaleff, MD
Claim this profileMaine Children's Cancer Program
Area of expertise
Brain Tumor
Stanley Chaleff, MD has run 4 trials for Brain Tumor. Some of their research focus areas include:
Low Grade Glioma
Stanley Chaleff, MD has run 3 trials for Low Grade Glioma. Some of their research focus areas include:
Affiliated Hospitals
Maine Children's Cancer Program
Clinical Trials Stanley Chaleff, MD is currently running
Selumetinib vs. Chemotherapy
for Brain Cancer
This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.
Recruiting
2 awards
Phase 3
Chemotherapy + Radiation Therapy
for Brain Cancer
This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting
1 award
Phase 2
More about Stanley Chaleff, MD
Clinical Trial Related
6 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Stanley Chaleff, MD has experience with
- Selumetinib
- Repotrectinib
- Carboplatin; Vincristine Sulfate
- Carboplatin; Vincristine
- Selumetinib Sulfate
- Vinblastine Sulfate
Breakdown of trials Stanley Chaleff, MD has run
Brain Tumor
Low Grade Glioma
Glioblastoma
Pancreatic Cancer
Anaplastic Large Cell Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Stanley Chaleff, MD specialize in?
Stanley Chaleff, MD focuses on Brain Tumor and Low Grade Glioma. In particular, much of their work with Brain Tumor has involved NTRK positive patients, or patients who are Stage IV.
Is Stanley Chaleff, MD currently recruiting for clinical trials?
Yes, Stanley Chaleff, MD is currently recruiting for 3 clinical trials in Scarborough Maine. If you're interested in participating, you should apply.
Are there any treatments that Stanley Chaleff, MD has studied deeply?
Yes, Stanley Chaleff, MD has studied treatments such as Selumetinib, Repotrectinib, Carboplatin; Vincristine Sulfate.
What is the best way to schedule an appointment with Stanley Chaleff, MD?
Apply for one of the trials that Stanley Chaleff, MD is conducting.
What is the office address of Stanley Chaleff, MD?
The office of Stanley Chaleff, MD is located at: Maine Children's Cancer Program, Scarborough, Maine 04074 United States. This is the address for their practice at the Maine Children's Cancer Program.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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