Stephen E. Spurgeon, MD

Dr. Stephen E. Spurgeon

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OHSU Knight Cancer Institute

Studies Mantle Cell Lymphoma
Studies Lymphoma
7 reported clinical trials
14 drugs studied

Area of expertise

1

Mantle Cell Lymphoma

Stephen E. Spurgeon has run 2 trials for Mantle Cell Lymphoma. Some of their research focus areas include:

CCND1 positive
t(11;14) positive
CD19 negative
2

Lymphoma

Stephen E. Spurgeon has run 2 trials for Lymphoma. Some of their research focus areas include:

Stage II
Stage III
Stage IV

Affiliated Hospitals

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OHSU Knight Cancer Institute

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Oregon Health And Science University

Clinical Trials Stephen E. Spurgeon is currently running

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Mosunetuzumab + Chemotherapy

for Diffuse Large B-Cell Lymphoma

This phase Ib/II clinical trial tests the safety, side effects, and effectiveness of mosunetuzumab with chemotherapy for the treatment of patients with untreated, c-Myc rearrangement positive, high grade B cell lymphoma or diffuse large B cell lymphoma. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as mosunetuzumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Chemotherapy drugs, such as etoposide, doxorubicin, vincristine, cyclophosphamide and prednisone work in different ways to stop the growth of cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving mosunetuzumab with chemotherapy may be safe, tolerable and/or effective in treating patients with untreated, c-Myc rearrangement positive, high grade B cell lymphoma or diffuse large B cell lymphoma.

Recruiting

1 award

Phase 1 & 2

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Triple Therapy

for Chronic Lymphocytic Leukemia

This phase Ib trial tests the safety and effectiveness of tafasitamab, acalabrutinib, and obinutuzumab in treating patients with previously untreated chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). CLL and SLL are types of cancer that develops from a specific white blood cell called B cells or B lymphocytes. Tafasitamab and obinutuzumab are monoclonal antibodies that may interfere with the ability of cancer cells to grow and spread. Acalabrutinib is in a class of medications called kinase inhibitors. It blocks a protein called BTK, which is present on B-cell cancers such as CLL at abnormal levels. This may help keep cancer cells from growing and spreading. Giving tafasitamab, acalabrutinib, and obinutuzumab may kill more cancer cells in patients with previously untreated CLL and SLL.

Recruiting

1 award

Phase 1

More about Stephen E. Spurgeon

Clinical Trial Related

7 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials

Treatments Stephen E. Spurgeon has experience with

  • Obinutuzumab
  • Ibrutinib
  • Acalabrutinib
  • Cytarabine
  • Glofitamab
  • Chemotherapy

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