Dr. Todd D. Tillmanns
Claim this profileThe West Clinic, PLLC dba West Cancer Center
Studies Cancer
Studies Endometrial Cancer
2 reported clinical trials
5 drugs studied
Affiliated Hospitals
Clinical Trials Todd D. Tillmanns is currently running
Selinexor Maintenance Therapy
for Endometrial Cancer
The purpose of this study is to evaluate the efficacy and safety of selinexor as a maintenance treatment in patients with p53 wt endometrial carcinoma (EC), who have achieved a partial response (PR) or complete response (CR) (per Response Evaluation Criteria in Solid Tumors version 1.1 \[RECIST v 1.1\]) after completing at least 12 weeks of platinum-based therapy. A total of 220 participants will be enrolled in the study and randomized in a 1:1 ratio to maintenance therapy with either selinexor or placebo.
Recruiting1 award Phase 32 criteria
Herceptin Hylecta or Phesgo + Chemotherapy
for Uterine Cancer
This phase II/III trial tests whether adding trastuzumab and hyaluronidase-oysk (Herceptin HylectaTM) or pertuzumab, trastuzumab and hyaluronidase-zzxf (PhesgoTM) to the usual chemotherapy (paclitaxel and carboplatin) works to shrink tumors in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma. Trastuzumab and pertuzumab are monoclonal antibodies and forms of targeted therapy that attach to specific molecules (receptors) on the surface of tumor cells, known as HER2 receptors. When trastuzumab or pertuzumab attach to HER2 receptors, the signals that tell the cells to grow are blocked and the tumor cell may be marked for destruction by the body's immune system. Hyaluronidase is an endoglycosidase. It helps to keep pertuzumab and trastuzumab in the body longer, so that these medications will have a greater effect. Hyaluronidase also allows trastuzumab and trastuzumab/pertuzumab to be given by injection under the skin and shortens their administration time compared to trastuzumab or pertuzumab alone. Paclitaxel is a taxane and in a class of medications called antimicrotubule agents. It stops cancer cells from growing and dividing and may kill them. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Giving Herceptin Hylecta or Phesgo in combination with paclitaxel and carboplatin may shrink the tumor and prevent the cancer from coming back in patients with HER2 positive endometrial serous carcinoma or carcinosarcoma.
Recruiting1 award Phase 2 & 3
More about Todd D. Tillmanns
Clinical Trial Related1 year of experience running clinical trials · Led 2 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Todd D. Tillmanns has experience with
- Selinexor
- Carboplatin
- Paclitaxel
- Pertuzumab
- Trastuzumab
Breakdown of trials Todd D. Tillmanns has run
Endometrial Cancer
Endometrial Carcinoma
Serous Cystadenocarcinoma
Mixed Mullerian Tumor
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Todd D. Tillmanns specialize in?
Todd D. Tillmanns focuses on Cancer and Endometrial Cancer. In particular, much of their work with Cancer has involved TP53 positive patients, or patients who are undergoing treatment.
Is Todd D. Tillmanns currently recruiting for clinical trials?
Yes, Todd D. Tillmanns is currently recruiting for 2 clinical trials in Germantown Tennessee. If you're interested in participating, you should apply.
Are there any treatments that Todd D. Tillmanns has studied deeply?
Yes, Todd D. Tillmanns has studied treatments such as Selinexor, Carboplatin, Paclitaxel.
What is the best way to schedule an appointment with Todd D. Tillmanns?
Apply for one of the trials that Todd D. Tillmanns is conducting.
What is the office address of Todd D. Tillmanns?
The office of Todd D. Tillmanns is located at: The West Clinic, PLLC dba West Cancer Center, Germantown, Tennessee 38138 United States. This is the address for their practice at the The West Clinic, PLLC dba West Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.