Dr. Wambui Machua
Claim this profilePiedmont Healthcare
Studies Lupus
Studies Systemic Lupus Erythematosus
7 reported clinical trials
17 drugs studied
Area of expertise
1Lupus
ANA positive
anti-Smith positive
dsDNA positive
2Systemic Lupus Erythematosus
Affiliated Hospitals
Clinical Trials Wambui Machua is currently running
Voclosporin + Mycophenolate Mofetil
for Lupus
The primary purpose of this study is to evaluate the potential effectiveness of 24 weeks of MMF within previously discovered immunologically defined subsets of SLE patients. Treatment effects will be evaluated within the individual immunologically-homogenous subsets defined at screening. This study will also explore and compare pre-randomization gene expression patterns among responders and non-responders to MMF and MMF plus voclosporin, use comprehensive immunophenotyping to study the immunologic changes that accompany treatment- induced disease improvement and to better understand immunologic changes associated with the loss of clinical response.
Recruiting0 awards Phase 21 criteria
Anifrolumab
for Lupus
This study to examines the impact of anifrolumab on disease activity, immune phenotypes, and development of neutralizing antibodies to quadrivalent influenza vaccine in patients with Systemic Lupus Erythematosus (SLE). 10 patients with moderately to severely active SLE will be treated with anifrolumab in addition to standard of care lupus treatments and 10 will receive only standard of care medications. All will receive influenza vaccine.
Recruiting0 awards Phase < 1
More about Wambui Machua
Clinical Trial Related1 year of experience running clinical trials · Led 7 trials as a Principal Investigator · 4 Active Clinical TrialsTreatments Wambui Machua has experience with
- Baricitinib
- Placebo
- BMS-986256 (Oral)
- Afimetoran
- TNF Inhibitor
- Voclosporin
Breakdown of trials Wambui Machua has run
Systemic Lupus Erythematosus
Arthritis
- Baricitinib for Rheumatoid Arthritis
- Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)
- Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs)
Rheumatoid Arthritis
- Baricitinib for Rheumatoid Arthritis
- Long-term Safety and Efficacy of GSK3196165 (Otilimab) in the Treatment of Rheumatoid Arthritis (RA)
- Efficacy and Safety of GSK3196165 Versus Placebo and Tofacitinib in Participants With Moderately to Severely Active Rheumatoid Arthritis Who Have an Inadequate Response to Conventional Synthetic (cs)/Biologic (b) Disease Modifying Anti-rheumatic Drugs (DMARDs)
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Wambui Machua specialize in?
Wambui Machua focuses on Lupus and Systemic Lupus Erythematosus. In particular, much of their work with Lupus has involved ANA positive patients, or patients who are anti-Smith positive.
Is Wambui Machua currently recruiting for clinical trials?
Yes, Wambui Machua is currently recruiting for 4 clinical trials in Atlanta Georgia. If you're interested in participating, you should apply.
Are there any treatments that Wambui Machua has studied deeply?
Yes, Wambui Machua has studied treatments such as Baricitinib, Placebo, BMS-986256 (Oral).
What is the best way to schedule an appointment with Wambui Machua?
Apply for one of the trials that Wambui Machua is conducting.
What is the office address of Wambui Machua?
The office of Wambui Machua is located at: Piedmont Healthcare, Atlanta, Georgia 30318 United States. This is the address for their practice at the Piedmont Healthcare.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.