Dr. Wenli GaO
Claim this profileDanbury Hospital
Studies Breast Cancer
Studies Cancer
8 reported clinical trials
20 drugs studied
Area of expertise
1Breast Cancer
HER2 positive
ER negative
PR negative
2Cancer
HER2 positive
ER positive
Stage IV
Affiliated Hospitals
Clinical Trials Wenli GaO is currently running
Pembrolizumab + Olaparib
for Pancreatic Cancer
This phase II trial studies whether adding pembrolizumab to olaparib (standard of care) works better than olaparib alone in treating patients with pancreatic cancer with germline BRCA1 or BRCA2 mutations that has spread to other places in the body (metastatic). BRCA1 and BRCA2 are human genes that produce tumor suppressor proteins. These proteins help repair damaged deoxyribonucleic acid (DNA) and, therefore, play a role in ensuring the stability of each cell's genetic material. When either of these genes is mutated, or altered, such that its protein product is not made or does not function correctly, DNA damage may not be repaired properly. As a result, cells are more likely to develop additional genetic alterations that can lead to some types of cancer, including pancreatic cancer. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Olaparib is an inhibitor of PARP, a protein that helps repair damaged DNA. Blocking PARP may help keep tumor cells from repairing their damaged DNA, causing them to die. PARP inhibitors are a type of targeted therapy. The addition of pembrolizumab to the usual treatment of olaparib may help to shrink tumors in patients with metastatic pancreatic cancer with BRCA1 or BRCA2 mutations.
Recruiting1 award Phase 237 criteria
Chemotherapy + Bevacizumab + Atezolizumab
for Colorectal Cancer
This phase III trial studies how well combination chemotherapy, bevacizumab, and/or atezolizumab work in treating patients with deficient deoxyribonucleic acid (DNA) mismatch repair colorectal cancer that has spread from where it first started (primary site) to other places in the body (metastatic). Chemotherapy drugs, such as fluorouracil, oxaliplatin, and leucovorin calcium, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Bevacizumab may stop or slow colorectal cancer by blocking the growth of new blood vessels necessary for tumor growth. Immunotherapy with monoclonal antibodies, such as atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving combination chemotherapy, bevacizumab, and atezolizumab may work better in treating patients with colorectal cancer.
Recruiting2 awards Phase 31 criteria
More about Wenli GaO
Clinical Trial Related5 years of experience running clinical trials · Led 8 trials as a Principal Investigator · 5 Active Clinical TrialsTreatments Wenli GaO has experience with
- Carboplatin
- Atezolizumab
- Paclitaxel
- Trastuzumab
- Pertuzumab
- Pembrolizumab
Breakdown of trials Wenli GaO has run
Breast Cancer
Cancer
Adenocarcinoma
Pancreatic Cancer
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Wenli GaO specialize in?
Wenli GaO focuses on Breast Cancer and Cancer. In particular, much of their work with Breast Cancer has involved HER2 positive patients, or patients who are ER negative.
Is Wenli GaO currently recruiting for clinical trials?
Yes, Wenli GaO is currently recruiting for 5 clinical trials in Danbury Connecticut. If you're interested in participating, you should apply.
Are there any treatments that Wenli GaO has studied deeply?
Yes, Wenli GaO has studied treatments such as Carboplatin, Atezolizumab, Paclitaxel.
What is the best way to schedule an appointment with Wenli GaO?
Apply for one of the trials that Wenli GaO is conducting.
What is the office address of Wenli GaO?
The office of Wenli GaO is located at: Danbury Hospital, Danbury, Connecticut 06810 United States. This is the address for their practice at the Danbury Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.