Dr. Yafen Liang, MD
Claim this profileThe University of Texas Health Science Center at Houston
Studies Acute Kidney Injury
Studies Unintentional Home Injuries
3 reported clinical trials
2 drugs studied
Affiliated Hospitals
Clinical Trials Yafen Liang, MD is currently running
Pantoprazole
for Acute Kidney Injury Prevention After Cardiac Surgery
The central hypothesis of this research study is that perioperative administration of the proton pump inhibitor (PPI) pantoprazole could reduce the development of acute kidney injury (AKI) following cardiac surgery by activation molecular pathways for kidney protection. The investigators propose a single-center, randomized, controlled, single-blinded trial to determine whether perioperative intravenous administration of pantoprazole will reduce some molecules that can be detected the urine, and major adverse kidney events (MAKE) at day 30 postoperatively, compared to famotidine after cardiac surgery. The specific aims of the study will be achieved by randomizing a group of 400 patients to receive pantoprazole (study) or famotidine (control) for 2 days perioperatively. Our study population will include any adult patients (aged over 18 years) scheduled for cardiac surgery requiring a cardiopulmonary bypass machine.
Recruiting3 awards Phase 41 criteria
Pantoprazole
for Acute Kidney Injury in Hemorrhagic Shock
The investigators propose a single-center, randomized, controlled trial to determine whether early initiation of proton pump inhibitor (PPI), pantoprazole, will decrease acute kidney injury (AKI) for trauma patients presenting with hemorrhagic shock compared to routine timing of initiation of PPI. Kidney injury will be assessed by the urinary kidney injury biomarkers, and the incidence, severity and AKI-free days within first week and major adverse kidney events (MAKE) at day 30. The specific aims of the study will be achieved by a cohort of 100 patients to receive either early(study) or routine (control) administration of pantoprazole for 2 days after the initial injury insult.
Recruiting1 award Phase 2 & 32 criteria
More about Yafen Liang, MD
Clinical Trial Related1 year of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Yafen Liang, MD has experience with
- Pantoprazole
- Famotidine
Breakdown of trials Yafen Liang, MD has run
Acute Kidney Injury
Unintentional Home Injuries
Hemorrhagic Shock
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Yafen Liang, MD specialize in?
Yafen Liang, MD focuses on Acute Kidney Injury and Unintentional Home Injuries. In particular, much of their work with Acute Kidney Injury has involved treating patients, or patients who are undergoing treatment.
Is Yafen Liang, MD currently recruiting for clinical trials?
Yes, Yafen Liang, MD is currently recruiting for 2 clinical trials in Houston Texas. If you're interested in participating, you should apply.
Are there any treatments that Yafen Liang, MD has studied deeply?
Yes, Yafen Liang, MD has studied treatments such as Pantoprazole, Famotidine.
What is the best way to schedule an appointment with Yafen Liang, MD?
Apply for one of the trials that Yafen Liang, MD is conducting.
What is the office address of Yafen Liang, MD?
The office of Yafen Liang, MD is located at: The University of Texas Health Science Center at Houston, Houston, Texas 77030 United States. This is the address for their practice at the The University of Texas Health Science Center at Houston.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.