Bipolar Disorder Clinical Trials in Cleveland

View 18 new treatments for Bipolar Disorder in Cleveland, OH near me. Every day, Power helps hundreds of Bipolar Disorder patients connect with leading medical research.
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Multiple Medications for Bipolar Depression

Research Clinic, Cleveland + 1 more

This trial is testing four different medications to find the best treatment for adults with bipolar disorder type 1 who are currently depressed. The medications work by balancing brain chemicals that affect mood. The goal is to help patients recover from depression and stay well.Show More
Waitlist

No Placebo Trial

Phase 4
Est. 4 - 6 Weeks
Unregistered Study Lead
Research Team

Iloperidone Safety for Adolescent Schizophrenia

Vanda Clinic, Garfield Heights + 2 more

To evaluate the safety and tolerability of iloperidone in adolescent patients with schizophrenia or bipolar I disorder for up to 52 weeks of treatment.
Recruiting

No Placebo Trial

Phase 4
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Cariprazine for Bipolar Disorder in Youth

AbbVie Clinic, Avon Lake + 1 more

This trial is testing the safety and effectiveness of Cariprazine for treating depressive episodes in children and teenagers with bipolar I disorder. The goal is to find out if Cariprazine can help young people with this condition. Cariprazine is an atypical antipsychotic recently approved for the treatment of depressive episodes in adults with bipolar I disorder.Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
ABBVIE INC.
Study Director

Lumateperone for Pediatric Bipolar Depression

Intra-Cellular Therapies Clinic, Avon Lake + 2 more

This is a multicenter, randomized, double-blind, placebo-controlled study in pediatric patients who are experiencing major depressive episodes (MDEs) associated with a primary diagnosis of bipolar I or bipolar II disorder as confirmed by Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL), according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5).Show More
Recruiting
Phase 3
Est. 6 - 12 Weeks
Unregistered Study Lead
Research Team

Dexmedetomidine for Agitation in Schizophrenia and Bipolar Disorder

BioXcel Clinic, Beachwood + 1 more

In this study, an investigational medication named BXCL501 is being tested for the treatment of episodes of agitation associated with bipolar I and bipolar II disorder, schizophrenia, schizoaffective and schizophreniform disorder. This study compares the study drug to a placebo.Show More
Recruiting
Phase 3
Est. 3 - 12 Weeks
Robert Risinger, MD
Study Chair

Cariprazine for Pediatric Schizophrenia

AbbVie Clinic, Avon Lake + 1 more

This trial is testing the safety and effectiveness of cariprazine in children and teens with schizophrenia, bipolar I disorder, or autism. The goal is to see if the medication is safe and beneficial for use in these young patients.Show More
Waitlist

No Placebo Trial

Phase 3
Est. 3 - 6 Weeks
ABBVIE INC.
Study Director

Lumateperone for Bipolar Mania

Intra-Cellular Therapies Clinic, North Canton + 1 more

This is a multicenter, randomized, double-blind, placebo-controlled, study in the acute treatment of patients with a diagnosis of bipolar I disorder with manic episodes or manic episodes with mixed features (bipolar mania), with or without psychotic symptoms, according to criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM 5).Show More
Recruiting
Phase 3
Est. 5 - 8 Weeks
Unregistered Study Lead
Research Team

Lurasidone for Cognitive Improvement in Bipolar Disorder

Research Clinic, Cleveland + 1 more

This trial is testing whether lurasidone can help improve thinking and memory in people with bipolar disorder who are currently stable but have cognitive problems. The medication works by balancing brain chemicals. Lurasidone has shown potential in improving thinking and memory in both schizophrenia and bipolar disorder.Show More
Recruiting
Phase 3
Est. 3 - 6 Weeks
Lakshmi N Yatham, MBBS,MRCPsy
Principal Investigator

BHV-7000 for Bipolar Disorder

Biohaven Clinic, North Canton + 1 more

The purpose of this study is to determine whether BHV-7000 is a safe and effective acute treatment for manic episodes in bipolar disorder I.
Recruiting
Phase 2 & 3
Est. 3 - 12 Weeks
Unregistered Study Lead
Research Team

Medical Cannabis for Chronic Pain

Research Clinic, Beechwood + 1 more

This trial will investigate if medical cannabis can effectively reduce pain and improve quality of life for patients with chronic conditions. The study will gather data through an online questionnaire about patients' use of cannabis and its effects. Medical cannabis interacts with the body's natural system to help manage pain and other symptoms. Medical cannabis has been increasingly studied and used as an alternative treatment for managing chronic pain, with numerous studies supporting its potential benefits.Show More
Recruiting

No Placebo Trial

Phase 2
Est. 6 - 12 Weeks
Dr. Ryan O Lakin, MD JD
Principal Investigator
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Frequently Asked Questions

How much do bipolar clinical trials pay?

Each trial will compensate patients a different amount, but $50-100 for each visit is a fairly common range. Further, most trials will cover the costs of an Uber to-and-from the clinic. Factors that can affect compensation include the phase of the trial, the length of the trial, the frequency of visits, and the specific condition being studied.

Do I need to be insured to participate in a medical study?

Clinical trials are almost always free to participants, and so do not require insurance. The only exception here are trials focused on Cancer, because only a small part of the typical treatment plan is actually experimental. For these cancer trials, participants typically need insurance to cover all the non-experimental components.

How do bipolar clinical trials work?

After a researcher reviews your profile, they may choose to invite you in to a screening appointment, where they'll determine if you meet 100% of the eligibility requirements. If you do, you'll typical be sorted into one of the treatment groups, and will receive your study drug. For some trials, there is a chance you'll receive a placebo. Across bipolar trials in Cleveland, 42% of clinical trials have a placebo. Typically you'll be required to check-in with the clinic every month or two. The average trial length in this city for bipolar patients is 6 Months.

What does the "phase" of a clinical trial mean?

The phase of a trial reveals what stage the drug is in getting approval for a specific condition. Phase 3 trials are in the final step before approval. The drug already has data showing both safety and effectiveness. Phase 2 trials are those where the drug has some data showing safety in humans, but where effectiveness has typically only been shown in animals and non-human experiments. Phase 1 trials are the trials where we don't have safety data in humans. As a general rule, phase 3 trials are more promising than phase 2, and phase 2 trials are more promising than phase 1.

What promising new drugs are being tested?

In Cleveland, research for bipolar disorder includes treatments like Mood Stabilizers and Atypical Antipsychotics. Specific drugs such as Lithium and Lurasidone are being studied.