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What is Lincomycin
LincomycinThe Generic name of this drug
Treatment SummaryLincomycin is an antibiotic used to treat bacterial infections. It was first discovered in the soil in Lincoln, Nebraska in 1906. The drug was approved by the FDA in 1964, but its use has mostly been replaced by its more powerful derivative, clindamycin. Despite this, lincomycin is still sometimes used to treat certain bacterial infections.
Lincocinis the brand name
Lincomycin Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Lincocin
Lincomycin
1964
15
Approved as Treatment by the FDA
Lincomycin, also called Lincocin, is approved by the FDA for 2 uses such as Serious Bacterial Infection and Bacterial Infections .Serious Bacterial Infection
Bacterial Infections
Effectiveness
How Lincomycin Affects PatientsLincomycin is an antibiotic taken from a type of bacteria called Streptomyces lincolnensis. It is used to treat bacterial infections, especially those caused by Staphylococcus and Streptococcus bacteria. It can also be used to treat some other types of bacteria, like Haemophilus, and some anaerobic bacteria. When taking lincomycin, care should be taken due to its potential side effects, such as severe skin reactions, colitis, and breathing problems in young children. Elderly patients, those with existing gastrointestinal problems, and those with a history of allergies or asthma
How Lincomycin works in the bodyLincomycin works by attaching to the bacterial ribosome, blocking it from making proteins. It uses an unusual amino acid-sugar combination to do this. This combination forms hydrogen bonds with certain parts of the ribosome, and also allows for a slight rotation of the sugar molecule. This rotation is what allows lincomycin to attach to the ribosome and block it from making proteins. Bacteria can develop resistance to lincomycin by modifying the part of the ribosome that lincomycin attaches to.
When to interrupt dosage
The suggested measure of Lincomycin is based upon the diagnosed condition. The quantity of dosage is contingent upon the technique of delivery (e.g. Injection, solution or Solution - Intramuscular; Intravenous) featured in the table beneath.Condition
Dosage
Administration
Bacterial Infections
, 300.0 mg/mL, 500.0 mg
, Intramuscular; Intravenous; Subconjunctival, Injection, solution, Injection, solution - Intramuscular; Intravenous; Subconjunctival, Capsule, Oral, Capsule - Oral, Intramuscular; Intravenous, Solution, Solution - Intramuscular; Intravenous, Injection, solution - Intramuscular; Intravenous
Warnings
Lincomycin has one contraindication, and it must not be utilized when encountering any of the conditions detailed in the following table.Lincomycin ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Lincomycin may interact with Pulse Frequency
Common Lincomycin Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Lincomycin.
Amineptine
Minor
Lincomycin may increase the neurotoxic activities of Amineptine.
Amisulpride
Minor
Lincomycin may increase the neurotoxic activities of Amisulpride.
Amitriptylinoxide
Minor
Lincomycin may increase the neurotoxic activities of Amitriptylinoxide.
Amperozide
Minor
Lincomycin may increase the neurotoxic activities of Amperozide.
Lincomycin Toxicity & Overdose RiskNot much is known about the effects of an overdose of lincomycin. However, it is known that it can cause severe side effects including stomach issues, secondary infections, and allergic reactions. To treat the overdose, supportive measures like dialysis should be taken. However, dialysis has little to no effect on the amount of lincomycin in the blood.
Lincomycin Novel Uses: Which Conditions Have a Clinical Trial Featuring Lincomycin?
An active study is evaluating the potential of Lincomycin to provide benefit for patients with Bacterial Infections.Condition
Clinical Trials
Trial Phases
Bacterial Infections
0 Actively Recruiting
Lincomycin Reviews: What are patients saying about Lincomycin?
3Patient Review
3/15/2010 This treatment really helped me. I'm grateful for modern medicine.
2.7Patient Review
1/13/2022 I started experiencing pain in my cheeks almost immediately after taking this medication. My gums are also swollen and pus-filled. This tablet has done more harm than good.
1Patient Review
7/13/2013 My pimples are still there.
Patient Q&A Section about lincomycin
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.What is the drug lincomycin used for?
"It will not work for viral infections (such as common cold, flu).
This medication is designed to treat a wide variety of bacterial infections by stopping the growth of bacteria. However, it will not work against infections caused by viruses such as the common cold or flu."
Answered by AI
What class of antibiotic is lincomycin?
"Lincomycin is an antibiotic. It belongs to the lincosamide class, which has a L-proline amino acid derivative linked to an eight-carbon aminothio sugar."
Answered by AI
What infections does lincomycin treat?
"An infection caused by bacteria, specifically Streptococcus, Staphylococcus, or Streptococcus pneumoniae."
Answered by AI
Is azithromycin a lincomycin?
"Lincocin (lincomycin) is an injectable antibiotic, which is not often used, that treats bacterial infections. Although generic forms of Zithromax (azithromycin) are available and the medication is good for treating a number of bacterial infections, side effects such as headache, dizziness, and rash may occur."
Answered by AI