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What is Meropenem
MeropenemThe Generic name of this drug
Treatment SummaryMeropenem is an antibiotic that fights both Gram-positive and Gram-negative bacteria. It works by entering the bacterial cells and stopping them from making the components they need to survive. In 2017, a combination of meropenem and another drug called [DB12107] was approved to treat complicated urinary tract infections in adults. This medication, called Vabomere, can help relieve symptoms and clear up the infection caused by susceptible bacteria.
Merrem IVis the brand name
Meropenem Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Merrem IV
Meropenem
1996
52
Approved as Treatment by the FDA
Meropenem, commonly known as Merrem IV, is approved by the FDA for 6 uses like Urinary Tract Infection (UTI) and Bacterial Infections .Urinary Tract Infection (UTI)
Bacterial Infections
Complicated Intra-Abdominal Infections (cIAIs)
Meningitis, Bacterial
Abdominal Infection
Communicable Diseases
Effectiveness
How Meropenem Affects PatientsMeropenem is an antibiotic that is effective against a wide range of bacteria, including both Gram-positive and Gram-negative. It works by entering the bacteria cells and disrupting their ability to make the components they need to survive, leading to their death.
How Meropenem works in the bodyMeropenem kills bacteria by blocking their ability to make cell walls. It works especially well on Gram-positive and Gram-negative bacteria, targeting specific proteins in the cells of these bacteria. Meropenem is especially effective at stopping the production of proteins in Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
When to interrupt dosage
The proposed dosage of Meropenem is contingent upon the determined affliction, including Urinary Tract Infection (UTI), complicated Bacterial Urinary Tract Infections and Meningitis, Bacterial. The measure of dosage relies upon the method of administration as demonstrated in the accompanying table.Condition
Dosage
Administration
Communicable Diseases
, 100.0 mg/mL, 50.0 mg/mL, 500.0 mg, 1000.0 mg, 1.0 mg/mg
, Intravenous, Injection, Injection - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, solution - Intravenous, Injection, solution
Meningitis, Bacterial
, 100.0 mg/mL, 50.0 mg/mL, 500.0 mg, 1000.0 mg, 1.0 mg/mg
, Intravenous, Injection, Injection - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, solution - Intravenous, Injection, solution
Abdominal Infection
, 100.0 mg/mL, 50.0 mg/mL, 500.0 mg, 1000.0 mg, 1.0 mg/mg
, Intravenous, Injection, Injection - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, solution - Intravenous, Injection, solution
Urinary Tract Infection (UTI)
, 100.0 mg/mL, 50.0 mg/mL, 500.0 mg, 1000.0 mg, 1.0 mg/mg
, Intravenous, Injection, Injection - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, solution - Intravenous, Injection, solution
Urinary Tract Infections
, 100.0 mg/mL, 50.0 mg/mL, 500.0 mg, 1000.0 mg, 1.0 mg/mg
, Intravenous, Injection, Injection - Intravenous, Injection, powder, for solution, Injection, powder, for solution - Intravenous, Powder, for solution, Powder, for solution - Intravenous, Injection, solution - Intravenous, Injection, solution
Warnings
Meropenem ContraindicationsCondition
Risk Level
Notes
Anaphylactic shock
Do Not Combine
Common Meropenem Drug Interactions
Drug Name
Risk Level
Description
Vibrio cholerae CVD 103-HgR strain live antigen
Major
The therapeutic efficacy of Vibrio cholerae CVD 103-HgR strain live antigen can be decreased when used in combination with Meropenem.
Abacavir
Minor
Meropenem may decrease the excretion rate of Abacavir which could result in a higher serum level.
Aclidinium
Minor
Meropenem may decrease the excretion rate of Aclidinium which could result in a higher serum level.
Acrivastine
Minor
Meropenem may decrease the excretion rate of Acrivastine which could result in a higher serum level.
Albutrepenonacog alfa
Minor
Meropenem may decrease the excretion rate of Albutrepenonacog alfa which could result in a higher serum level.
Meropenem Toxicity & Overdose RiskLarge doses of meropenem have been known to cause coordination problems, difficulty breathing, seizures, and death in mice and rats.
Meropenem Novel Uses: Which Conditions Have a Clinical Trial Featuring Meropenem?
27 active clinical trials are being conducted to investigate the potential of Meropenem to treat Meningitis, Bacterial Abdominal Infection, and Urinary Tract Infections (UTI).Condition
Clinical Trials
Trial Phases
Meningitis, Bacterial
0 Actively Recruiting
Abdominal Infection
0 Actively Recruiting
Communicable Diseases
0 Actively Recruiting
Urinary Tract Infections
0 Actively Recruiting
Urinary Tract Infection (UTI)
9 Actively Recruiting
Phase 1, Phase 3, Phase 4, Not Applicable
Meropenem Reviews: What are patients saying about Meropenem?
5Patient Review
4/7/2013 This antibiotic was very effective, but it may be too costly for some people. Make sure to use it as directed, and the infection will be cured in no time.
4.3Patient Review
10/8/2012 This medication made me very tired. I was hospitalized after taking it for about two weeks.
4Patient Review
5/6/2009 The only drawback was having to mix the solution each time before using it.
3.7Patient Review
10/1/20072.7Patient Review
5/30/2018 I've been feeling really ill since taking this medication. I have no energy, and I'm constantly nauseated and have diarrhea. Not to mention the headaches. I haven't seen any benefits yet, but that's why I only gave it 2.7 stars.
Patient Q&A Section about meropenem
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is meropenem the strongest antibiotic?
"Meropenem is considered a stronger antibiotic compared to other options. It is effective against many types of bacteria and can treat severe or complicated infections when other antibiotics are not effective. However, it is important to keep in mind that "stronger" antibiotics are not always the best choice."
Answered by AI
What meropenem is used for?
"Meropenem is used to treat bacterial infections. It works by killing bacteria or preventing their growth. It will not work for infections caused by viruses, such as colds or flu."
Answered by AI
What type of antibiotic is meropenem?
"Meropenem is a drug that is used to treat a broad range of serious infections in both adults and children. It is from the carbapenem family, which is a broad-spectrum antibacterial agent. Meropenem is indicated as empirical therapy, which means that it is given before the exact cause of the infection is known."
Answered by AI
Is meropenem a penicillin?
"Meropenem is an antibiotic that is effective against many of the same infections as penicillin. However, since meropenem and penicillins have similar chemical structures, doctors often avoid using meropenem in patients who are allergic to penicillin."
Answered by AI