Metrocream

Pouchitis, Liver Abscess, Amebic, Lung Abscess + 53 more

Treatment

41 FDA approvals

20 Active Studies for Metrocream

What is Metrocream

Metronidazole

The Generic name of this drug

Treatment Summary

Metronidazole is a type of antibiotic used to treat bacterial and parasitic infections in the gastrointestinal tract, such as trichomoniasis and giardiasis. It has been used for several decades, and is available in various forms, including capsules, tablets, topical creams, and suppositories. Metronidazole is a popular antibiotic due to its ability to treat a wide range of infections.

Flagyl

is the brand name

image of different drug pills on a surface

Metrocream Overview & Background

Brand Name

Generic Name

First FDA Approval

How many FDA approvals?

Flagyl

Metronidazole

1963

449

Approved as Treatment by the FDA

Metronidazole, commonly known as Flagyl, is approved by the FDA for 41 uses including Abscess and Bone and Joint Infections .

Abscess

Bone and Joint Infections

Liver Abscess

Communicable Diseases

Osteomyelitis

Bacterial Endocarditis

Helicobacter Pylori Infection

Used to treat Helicobacter Pylori Infection in combination with Bismuth subsalicylate

Abdominal Abscess

Abdominal Infection

Skin and skin structure infections

Gynaecological infection

Lung Abscess

Endometritis

Central Nervous System Bacterial Infections

Bacterial Meningitis

Pneumonia

intra-abdominal bacterial infections

hepatic abscess

Tubo-ovarian abscess

Lung Abscess

Curling Ulcer

Used to treat Duodenal Ulcer in combination with Bismuth subsalicylate

Lower respiratory tract infection bacterial

Bacterial Septicemia

Bacteria, Anaerobic

Bacterial Infections

Duodenal Ulcer

Used to treat Duodenal Ulcer in combination with Bismuth subsalicylate

Meningitis

Abscess, Intra-Abdominal

Empyema

asymptomatic Trichomoniasis

Exposure via partner

Endomyometritis

Bacterial Peritonitis

Central Nervous System Bacterial Infections

Empyema

Trichomonas Infections

Endometritis

Endometritis

Bacteria

Endocarditis, Bacterial

Communicable Diseases

Effectiveness

How Metrocream Affects Patients

Metronidazole is an antibiotic and antiprotozoal medicine used to treat certain infections. It usually works against anaerobic bacteria and protozoa, but does not work as well against facultative anaerobes or obligate aerobes. Metronidazole can cause serious side effects, including convulsions and peripheral neuropathy, so it should only be used when absolutely necessary. There is also evidence that it may cause cancer in mice and rats, but it is unknown if this applies to humans.

How Metrocream works in the body

Metronidazole works by targeting the cells of certain bacteria and parasites. It is able to enter their cells and interact with the electron transport proteins and DNA, preventing them from replicating. Metronidazole is only effective against anaerobic or microaerophilic organisms, meaning it is only effective against certain types of bacteria and parasites. It produces toxic metabolites that damage the DNA of these organisms, ultimately leading to cell death.

When to interrupt dosage

The measure of Metrocream is contingent upon the diagnosed affliction, including Exposure via partner, Skin and Curling Ulcer. The quantity of dosage is contingent upon the strategy of delivery (e.g. Capsule or Vaginal) featured in the table below.

Condition

Dosage

Administration

Bacterial Vaginosis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Bacterial Septicemia

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Bacterial Peritonitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Tubo-ovarian abscess

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Vaginitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Trichomonas Vaginitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

post-surgical vaginal cuff infection

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Inflammatory Papule

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Pouchitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Giardiasis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Vulvovaginitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Uterine Cervicitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Exposure via partner

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Communicable Diseases

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Candida albicans

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Bacterial Meningitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Sinusitis

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Endocarditis, Bacterial

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Operative Surgical Procedures

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Lockjaw

5.0 mg/mL, , 0.0075 mg/mg, 500.0 mg, 0.01 mg/mg, 7.5 mg/mL, 250.0 mg, 375.0 mg, 0.065 mg/mg, 125.0 mg, 10.0 %, 0.75 %, 1.0 %, 750.0 mg, 0.001 mg/mg, 200.0 mg, 400.0 mg, 100.0 mg/mL, 0.013 mg/mg, 0.5 mg/mg

Injection, solution, Injection, solution - Intravenous, Intravenous, , Gel - Topical, Topical, Gel, Oral, Tablet, Cream, Cream - Topical, Tablet - Oral, Lotion - Topical, Lotion, Solution - Intravenous, Tablet, film coated, Tablet, film coated - Oral, Capsule, Capsule - Oral, Vaginal, Gel - Vaginal, Cream - Vaginal, Suppository - Vaginal, Suppository, Suppository - Rectal, Rectal, Injection - Intravenous, Kit, Kit - Oral, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Ointment, Ointment - Topical, Insert - Vaginal, Insert, Solution, Tablet, extended release - Oral, Tablet, extended release, Tablet, coated, Tablet, coated - Oral

Warnings

Metrocream has three contraindications and should not be utilized when dealing with the conditions listed in the following table.

Metrocream Contraindications

Condition

Risk Level

Notes

Severe Hypersensitivity Reactions

Do Not Combine

Metronidazole may interact with Pulse Frequency

Pregnancy Trimester, First

Do Not Combine

Severe Hypersensitivity Reactions

Do Not Combine

Metronidazole may interact with Pulse Frequency

There are 20 known major drug interactions with Metrocream.

Common Metrocream Drug Interactions

Drug Name

Risk Level

Description

Abemaciclib

Major

The metabolism of Abemaciclib can be decreased when combined with Metronidazole.

Acalabrutinib

Major

The metabolism of Acalabrutinib can be decreased when combined with Metronidazole.

Alectinib

Major

The metabolism of Alectinib can be decreased when combined with Metronidazole.

Alpelisib

Major

The metabolism of Alpelisib can be decreased when combined with Metronidazole.

Aminophylline

Major

The metabolism of Aminophylline can be decreased when combined with Metronidazole.

Metrocream Toxicity & Overdose Risk

The toxic dose of metronidazole in rats is 5000 mg/kg. Overdosing on metronidazole can cause symptoms such as nerve damage, brain toxicity, seizures, reactions to alcohol, dark urine, a bad metallic taste in the mouth, nausea, stomach pain, and dizziness, as well as lowered immune system function. There is no antidote for a metronidazole overdose, so it is important to seek medical attention and administer activated charcoal to help absorb the drug in the stomach. Contacting your local poison control center is also recommended.

image of a doctor in a lab doing drug, clinical research

Metrocream Novel Uses: Which Conditions Have a Clinical Trial Featuring Metrocream?

Research is currently being conducted on 179 active studies to assess the effectiveness of Metrocream in treating Curling Ulcer, Periodontitis and Central Nervous System Bacterial Infections.

Condition

Clinical Trials

Trial Phases

Lockjaw

0 Actively Recruiting

Uterine Cervical Erosion

0 Actively Recruiting

Gum Disease

3 Actively Recruiting

Phase 3, Not Applicable

Abdominal Infection

0 Actively Recruiting

Rosacea

0 Actively Recruiting

Balantidiasis

0 Actively Recruiting

Empyema

1 Actively Recruiting

Phase 4

Abdominal Abscess

2 Actively Recruiting

Phase 4, Phase 1, Phase 2

Bacteria

0 Actively Recruiting

Trichomonas Infections

0 Actively Recruiting

Vulvovaginitis

0 Actively Recruiting

Lung Abscess

0 Actively Recruiting

Pouchitis

5 Actively Recruiting

Phase 2, Phase 3, Early Phase 1, Phase 4

Atopic Dermatitis

12 Actively Recruiting

Phase 2, Phase 3, Phase 4, Not Applicable

Acne Vulgaris

0 Actively Recruiting

Operative Surgical Procedures

0 Actively Recruiting

Liver Abscess, Amebic

0 Actively Recruiting

Trichomonas Vaginitis

2 Actively Recruiting

Phase 2, Phase 4

Amebic colitis

0 Actively Recruiting

Rosacea

2 Actively Recruiting

Early Phase 1, Phase 2

Metrocream Reviews: What are patients saying about Metrocream?

5

Patient Review

5/17/2010

Metrocream for Acne Rosacea

I had severe acne rosacea and this treatment has virtually eliminated the problem. I couldn't be happier with the results!

5

Patient Review

2/7/2017

Metrocream for Acne Rosacea

MetroCream has done wonders for my rosacea. I've been using it for two years now, and although I still get the occasional flare-up, this cream keeps my skin looking healthy most of the time. A couple weeks is all it took to start seeing results, and I would definitely recommend it to others struggling with rosacea.

4.7

Patient Review

7/3/2011

Metrocream for Acne Rosacea

I applied the cream to my face every night before bed, and it took a few days for the lumps to go away. Highly effective in reducing redness from rosacea.

4.7

Patient Review

12/1/2013

Metrocream for Acne Rosacea

After using this cream on and off for three weeks, I've seen significant results that have only gotten better with time. After one week of using it twice daily, the redness on my cheeks was reduced and the bumps on my chin and cheeks had all but disappeared. There's still some redness on my chin, but it's barely noticeable.

4.3

Patient Review

11/11/2008

Metrocream for Acne Rosacea

This cream has been very effective at reducing the redness on my forehead. However, it only lasts for a few hours, so I'm going to start using it twice a day instead of just once.

3

Patient Review

12/31/2012

Metrocream for Acne Rosacea

I didn't see a huge difference in the redness, but it wasn't bad enough to bother me.

2

Patient Review

5/24/2018

Metrocream for Acne Rosacea

Even with insurance, this medication is quite costly. Unfortunately, it also doesn't work. I applied it twice daily for three months with no improvement whatsoever. In fact, my skin looked more greasy and bumpy than before. I decided to try Prosacea instead (which only cost $8), and saw amazing results immediately! The itching stopped and the bumps decreased significantly within just a few days.

1

Patient Review

4/18/2011

Metrocream for Acne Rosacea

Unfortunately, I had a severe reaction to this cream. My face turned red and started swelling up. I had to go to the hospital and get medication for the swelling.
image of drug pills surrounding a glass of water symbolizing drug consumption

Patient Q&A Section about metrocream

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Can Metrocream make rosacea worse?

"The cream burns my skin and feels more like putting on gelatinous fire than an antibiotic cream. It also seems to make the Rosacea worse. Finally, it is very expensive."

Answered by AI

Is Metrocream a prescription?

"Rosacea is a condition that causes redness and swelling on the face. MetroCream is a prescription medicine that can help to treat the symptoms of Rosacea."

Answered by AI

What is Metrocream used for?

"This medication is used on the skin to treat a certain skin disorder known as rosacea, a type of adult acne. It may help improve the appearance of the skin by reducing redness, swelling and the number of pimples caused by rosacea. This medication is an antibiotic."

Answered by AI

Is Metrocream antifungal?

"The side effects of metronidazole and miconazole are similar, including skin rash."

Answered by AI

Clinical Trials for Metrocream

Image of ALS Global in Irving, United States.

GX-03 for Eczema

18 - 70
All Sexes
Irving, TX

This is a randomized, double-blind, vehicle-controlled clinical study designed to evaluate the efficacy and safety of GX-03, a topically applied emollient, in adult subjects with moderate to severe eczema. Approximately 120 adult participants will be enrolled and randomized in a 1:1 ratio to receive either GX-03 or a petrolatum-based vehicle control for 8 consecutive weeks. Efficacy will be assessed using validated clinical outcome measures, including the Eczema Area and Severity Index (EASI), the Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD™), and the Peak Pruritus Numeric Rating Scale (PP-NRS). Safety will be evaluated through monitoring of treatment-emergent adverse events throughout the study period.

Phase 2
Recruiting

ALS Global

Turn Therapeutics

Image of Seeding Labs INC in Austin, United States.

Tailored Recommendations for Infant Gut Microbiome

No minimum age - 3
All Sexes
Austin, TX

The goal of this clinical trial is to learn whether microbiome analysis, education, and personalized recommendations can improve gut health and reduce early markers of immune-related conditions in infants aged 0-3 months delivered via Cesarean section. The study aims to determine whether these interventions can increase beneficial bacteria, decrease C-section-associated microbiome signatures, reduce opportunistic pathogens, and improve functional potential for HMO digestion and SCFA production. The study also seeks to assess whether improvements in microbiome composition are associated with a reduced prevalence of early atopic symptoms. Researchers will compare three groups: a full intervention arm that receives microbiome reports, coaching, personalized recommendations, and educational materials; a limited intervention arm that receives simplified reports and basic recommendations; and a control arm that receives no results until study completion. This design allows evaluation of both a comprehensive intervention and a more scalable, minimal-results model. Participants will: 1. Provide six microbiome stool samples over a 24-month period. 2. Provide additional small stool samples at two timepoints for exploratory metabolomic analysis. 3. Receive microbiome reports and guidance according to their assigned study arm. 4. Complete surveys on infant health history, symptoms, diet, and environmental exposures. 5. Participate in standardized eczema assessment(s) administered by a Nurse Practitioner and evaluated by a Pediatric Allergy Specialist if any symptoms are reported. This study seeks to demonstrate that targeted microbiome support can positively shift gut microbial development in C-section infants and may reduce risks linked to the early stages of the atopic march. Findings may inform scalable strategies for delivering microbiome-based support in early life and improve long-term health outcomes for this high-risk population.

Waitlist Available
Has No Placebo

Seeding Labs INC

Qian Yuan, MD

Seeding, Inc DBA Tiny Health

Image of Children's of Alabama in Birmingham, United States.

Antibiotic Duration for Infections in Children

60 - 17
All Sexes
Birmingham, AL

Infections like pneumonia, skin and soft tissue infection (also called SSTI or cellulitis), and urinary tract infections (UTI) are some of the most common reasons children get admitted to the hospital. All three of these conditions require antibiotics for treatment. Although antibiotics are needed to treat the infection and help children feel better, taking them longer than needed can negatively impact children and their families. Negative impacts include things like the burdens of taking more medications and medication side effects. There are guidelines (instructions) from expert medical organizations that suggest the number of days children need antibiotics, but they give a wide range (between 5 and 14 days). Unfortunately, these guidelines are not based on high-quality studies. National data suggests that doctors often choose on the higher end of this range when writing prescriptions for children in the hospital. Our three caregiver co-investigators, other parents of hospitalized children, doctors, other care providers, and researchers, all believe that additional study is needed to determine the best length of antibiotic treatment that weighs both the benefits and harms of antibiotics. The goal of our study is to understand if 5 total days of antibiotic treatment compared to 10 total days of antibiotic treatment is better for children who have been in the hospital for pneumonia, SSTI, or UTI. We will study this question through a randomized control trial. In other words, half of the children will receive 5-days of antibiotics and the other half will receive 10-days of antibiotics. Children in this study (and their caregivers) will not know how many days of antibiotics they will receive to cure their infection because some children will take a placebo (or a pill without antibiotics in it). Only the pharmacy will know if a child is getting antibiotic or placebo (for days 6-10 of treatment). During the first phase of the trial (feasibility phase), 4 hospitals will enroll children in the study. We plan on enrolling 50 patients during this phase. We are starting with just 4 hospitals, so our study team can create and update our study plans if needed. We will closely review information about how many patients and families agree to participate, and if they have any trouble completing any part of the study. We will also interview families to understand the choice to participate in the study, the choice not to participate in the study, and what it is like to be in the study. During the second study phase, we will enroll 1150 more patients across all 11 hospitals. Families will complete short, daily surveys until the 15th day after they started antibiotics, then a larger survey at day 15, at day 20, and at day 30. These surveys will ask about the child's symptoms and recovery from their illness, how the antibiotics are making them feel, and if they had to go back to their doctor, emergency room, or hospital. The answers to these questions will be combined to measure how well the child did, balancing feeling better and having bad effects from the antibiotics. We will use mathematical tests to determine which antibiotic duration is better for treating these illnesses. We will complete other mathematical tests to see if all children should receive the same length of antibiotics or if certain children should be prescribed shorter courses and others longer courses.

Phase 4
Waitlist Available

Children's of Alabama (+9 Sites)

Sunitha V Kaiser, MD, MSc

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Image of UNC Chapel Hill in Chapel Hill, United States.

Intrapleural Enzyme Therapy for Pleural Infection

18+
All Sexes
Chapel Hill, NC

The goal of this clinical trial is to find out if giving certain medications once a day works just as well as giving them twice a day to treat infections around the lungs (called pleural infections). These medications-tissue plasminogen activator (tPA) and deoxyribonuclease (DNase)-are placed through a chest tube into the space between the lung and the chest wall to help clear out the infection. The investigators are trying to learn: * Does using the medicine once a day work just as well as using it twice a day? * Are there any differences in outcomes between patients who get the medicine once a day versus twice a day? * Does more or less fluid remain in the chest (seen on a chest x-ray) depending on how often the medicine is given? Participants will: * Have an infection around their lung and will already be getting normal hospital care, including a chest tube to drain the infected fluid around their lung. * Be asked to give permission to join the study. * Be randomly chosen (like flipping a coin) to get the medications either once a day or twice a day through the chest tube.

Phase 4
Waitlist Available

UNC Chapel Hill

Jason Akulian, MD, MPH

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We made a collection of clinical trials featuring Metrocream, we think they might fit your search criteria.
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Image of Office of Dental Health, Department of Health and Senior Services in Jefferson City, United States.

Dental Care for Pneumonia Prevention

60 - 100
All Sexes
Jefferson City, MO

The goal of this study is to learn if dental infection control treatment delivered to older adult nursing home residents at their place of residence will result in : * improved dental health * reduced risk of pneumonia * better glucose control for diabetic patients compared to the pre-project dental and general health evaluations of residents and the pre-project facility incidence of pneumonia. Dental infection control treatment includes treating gum infections, stopping or slowing decay with fluoride, and assisting residents with effective tooth brushing and denture cleaning daily. Previous studies indicate dental infections can be inhaled and cause pneumonia or make diabetes worse. A shortage of dentists has limited care for nursing home residents. This project will allow dental hygienists and specially trained dental assistants to treat nursing home residents using telehealth methods (computers, cameras, internet, and telephone) to talk and work with dentists in different locations.

Recruiting
Has No Placebo

Office of Dental Health, Department of Health and Senior Services

Have you considered Metrocream clinical trials?

We made a collection of clinical trials featuring Metrocream, we think they might fit your search criteria.
Go to Trials