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What is Naprelan
NaproxenThe Generic name of this drug
Treatment SummaryNaproxen is a pain reliever and anti-inflammatory medication that was first introduced in 1976 as a prescription drug and then approved for over-the-counter use in 1994. It can be used to treat acute pain, rheumatic diseases, and migraines. Naproxen is generally well tolerated and is often prescribed as the first treatment option for pain relief. It is available in immediate and delayed release forms, as well as in combination with other medications (sumatriptan and esomeprazole) to provide additional benefits.
Naprosynis the brand name
Naprelan Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Naprosyn
Naproxen
1976
1260
Approved as Treatment by the FDA
Naproxen, otherwise known as Naprosyn, is approved by the FDA for 18 uses including Juvenile arthritis and Migraine .Juvenile arthritis
Used to treat Juvenile Idiopathic Arthritis (JIA) in combination with Esomeprazole
Migraine
Inflammation
Used to treat articular inflammation in combination with Esomeprazole
Back
Ankylosing Spondylitis
Used to treat Ankylosing Spondylitis (AS) in combination with Esomeprazole
Dysmenorrhea
Osteoarthritis
Used to treat Osteoarthritis (OA) in combination with Esomeprazole
articular inflammation
Used to treat articular inflammation in combination with Esomeprazole
Acute Coryza
Used to treat Acute Migraine in combination with Sumatriptan
Osteoarthritis (OA)
Used to treat Osteoarthritis (OA) in combination with Esomeprazole
Rheumatoid Arthritis
Used to treat Rheumatoid Arthritis in combination with Esomeprazole
Back pain
Headache
Menstrual Distress (Dysmenorrhea)
Ankylosing Spondylitis (AS)
Used to treat Ankylosing Spondylitis (AS) in combination with Esomeprazole
Juvenile Idiopathic Arthritis (JIA)
Used to treat Juvenile Idiopathic Arthritis (JIA) in combination with Esomeprazole
Toothache
Fever
Effectiveness
How Naprelan Affects PatientsNaproxen is a type of painkiller that reduces inflammation and fever. It works by blocking a certain enzyme (cyclo-oxygenase) that helps produce a type of chemical (prostaglandin) that can cause pain and swelling. While naproxen can effectively reduce pain, it can also lead to an increase in blood pressure and an increased risk of upper gastrointestinal bleeding. Taking other medications such as corticosteroids or anticoagulants at the same time as naproxen can increase the risk of upper gastrointestinal bleeding, as well as having a history of gastrointestinal ulcers.
How Naprelan works in the bodyNaproxen works by blocking two enzymes, COX-1 and COX-2. COX-1 is a normal enzyme found in the stomach lining, while COX-2 is an enzyme that produces prostaglandins involved in pain, fever, and inflammation. By blocking these enzymes, naproxen reduces prostaglandin production, which helps reduce pain, fever, and inflammation. However, it also blocks the COX-1 enzyme, which can cause side effects like gastrointestinal upset and kidney problems.
When to interrupt dosage
The prescribed measure of Naprelan is contingent upon the identified condition, including Menstrual Distress (Dysmenorrhea), Migraine and Toothache. The dosage fluctuates as per the mode of delivery (e.g. Tablet, extended release or Tablet, delayed release) detailed in the table beneath.Condition
Dosage
Administration
Inflammation
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Toothache
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Chronic Pain
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Migraine
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Sinusitis
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Migraine
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Fever
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Influenza
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Migraine Disorders
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Arthritis, Gouty
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Hay Fever
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Rheumatoid Arthritis
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Arthritis, Juvenile
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Dysmenorrhea
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Juvenile arthritis
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Ankylosing Spondylitis
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Osteoarthritis
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Epilepsy, Post-Traumatic
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Back
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Primary Dysmenorrhoea
125.0 mg/mL, , 220.0 mg, 200.0 mg, 550.0 mg, 275.0 mg, 500.0 mg, 750.0 mg, 375.0 mg, 250.0 mg, 5.0 mg/mg, 125.0 mg, 60.0 mg, 1000.0 mg, 2.2 mg/mg, 1.0 mg/mg, 210.0 mg, 105.0 mg, 50.0 mg/mL, 25.0 mg/mL
Oral, , Suspension, Suspension - Oral, Tablet, film coated, Tablet, film coated - Oral, Capsule, liquid filled, Capsule, liquid filled - Oral, Tablet, Tablet - Oral, Topical, Kit, Kit - Topical, Tablet, film coated, extended release, Tablet, film coated, extended release - Oral, Tablet, delayed release, Tablet, delayed release - Oral, Capsule, Capsule - Oral, Tablet, coated, Tablet, coated - Oral, Kit - Oral, Rectal, Suppository - Rectal, Suppository, Tablet, extended release, Tablet, extended release - Oral, Cream - Topical, Tablet, for suspension, Tablet, for suspension - Oral, Tablet, multilayer, extended release - Oral, Tablet, multilayer, extended release, Kit - Oral; Topical, Oral; Topical
Warnings
Naprelan has four contraindications and should not be utilized when enduring the conditions in the following table.Naprelan ContraindicationsCondition
Risk Level
Notes
Coronary Artery Bypass Grafting
Do Not Combine
Severe Hypersensitivity Reactions
Do Not Combine
Naproxen may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Naproxen may interact with Pulse Frequency
Severe Hypersensitivity Reactions
Do Not Combine
Naproxen may interact with Pulse Frequency
Common Naprelan Drug Interactions
Drug Name
Risk Level
Description
Amiodarone
Major
The metabolism of Amiodarone can be decreased when combined with Naproxen.
Brigatinib
Major
The metabolism of Brigatinib can be decreased when combined with Naproxen.
Cabazitaxel
Major
The metabolism of Cabazitaxel can be decreased when combined with Naproxen.
Enasidenib
Major
The metabolism of Enasidenib can be decreased when combined with Naproxen.
Erlotinib
Major
The metabolism of Erlotinib can be decreased when combined with Naproxen.
Naprelan Toxicity & Overdose RiskNaproxen is available without a prescription, but this increases the chances of an overdose. Generally, the effects of such an overdose are minor, including drowsiness, fatigue, stomach pain, and nausea and vomiting. No specific antidote exists for naproxen overdose, however the symptoms should disappear with proper care. Naproxen should not be taken by pregnant women during their third trimester as it may lead to the early closure of the fetus's ductus arteriosus.
Naprelan Novel Uses: Which Conditions Have a Clinical Trial Featuring Naprelan?
635 active trials are currently underway to investigate the potential of Naprelan to relieve Chronic Pain, Migraine and Juvenile Rheumatoid Arthritis.Condition
Clinical Trials
Trial Phases
Arthritis, Gouty
0 Actively Recruiting
Fever
2 Actively Recruiting
Phase 4, Not Applicable
Influenza
39 Actively Recruiting
Not Applicable, Phase 4, Phase 2, Phase 3, Phase 1
Bursitis
0 Actively Recruiting
Migraine
14 Actively Recruiting
Phase 2, Not Applicable, Phase 4, Phase 1, Phase 3
Arthritis, Juvenile
2 Actively Recruiting
Not Applicable
Migraine
51 Actively Recruiting
Phase 4, Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1
Inflammation
0 Actively Recruiting
Chronic Pain
150 Actively Recruiting
Not Applicable, Phase 1, Phase 2, Phase 4, Phase 3, Early Phase 1
Collagen Diseases
0 Actively Recruiting
Spasm
0 Actively Recruiting
Nasal Congestion
0 Actively Recruiting
Rheumatoid Arthritis
54 Actively Recruiting
Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1
Juvenile arthritis
12 Actively Recruiting
Phase 2, Phase 1, Not Applicable, Phase 3
Osteoarthritis
0 Actively Recruiting
Back
8 Actively Recruiting
Not Applicable, Phase 3, Early Phase 1, Phase 2, Phase 4, Phase 1
Acute Coryza
0 Actively Recruiting
Epilepsy, Post-Traumatic
0 Actively Recruiting
Tendinopathy
0 Actively Recruiting
Primary Dysmenorrhoea
1 Actively Recruiting
Not Applicable
Naprelan Reviews: What are patients saying about Naprelan?
5Patient Review
4/29/20095Patient Review
5/31/20095Patient Review
6/11/20095Patient Review
7/5/2011 One unfortunate side effect is hair loss.
5Patient Review
7/20/2012 This medication really helped my arthritis. I didn't experience any negative side effects, and only having to take it once a day was great.
Patient Q&A Section about naprelan
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.How strong of a painkiller is naproxen?
"The naproxen content in each of these varies. The regular naproxen tablets contain 250mg, 375mg, or 500mg of naproxen. The fast-absorbing naproxen sodium is available in 220mg OTC capsules and tablets, and 275mg and 550mg tablets prescribed by a doctor."
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Is Naprelan the same as naproxen?
"NAPRELAN (naproxen sodium) is a nonsteroidal anti-inflammatory drug. It is available in 375 mg, 500 mg, and 750 mg strengths for oral administration."
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How much does Naprelan cost?
"The cost of one hundred Naprelan oral tablets, extended release (375 mg (as sodium)) varies depending on the pharmacy, but is typically around $2,303 for cash paying customers who do not have insurance."
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