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What is Patanase
OlopatadineThe Generic name of this drug
Treatment SummaryOlopatadine is a medication used to treat allergic reactions and inflammation. It works by blocking the effects of histamine, a chemical released during an allergic reaction. Olopatadine is available as an eye drop solution for the treatment of seasonal and perennial allergic conjunctivitis and a nasal spray for the treatment of seasonal allergic rhinitis. It is typically well-tolerated, causing few side effects. Olopatadine is sold under the brand names Pazeo, Patanase, and Opatanol.
Patanolis the brand name
Patanase Overview & Background
Brand Name
Generic Name
First FDA Approval
How many FDA approvals?
Patanol
Olopatadine
1997
124
Effectiveness
How Patanase Affects PatientsOlopatadine is a medication used to treat allergy symptoms like itching, redness, swelling, and tearing of the eyes. It works by blocking the effects of histamine, a molecule responsible for triggering allergies. Pre-clinical studies and human trials have shown that olopatadine works quickly and can last for up to 24 hours. While it is generally a non-sedating medication, some people may experience drowsiness after taking it. It also has negligible effects on other types of receptors in the body and does not seem to affect the QT interval.
How Patanase works in the bodyHistamine is a natural chemical that causes inflammation when it binds to its receptors. Histamine activates a series of reactions in the cells that release cytokines and other inflammatory mediators, resulting in allergy symptoms. Olopatadine is a drug that stops histamine from binding to its receptor and triggering inflammation. It also blocks the signals sent out by the receptor, preventing the release of cytokines and other mediators. Olopatadine also stops cells from sticking together, which reduces inflammation. In addition, it stops cells involved in inflammation from becoming activated.
When to interrupt dosage
The proposed dose of Patanase is contingent upon the specified sickness, including Hay Fever, Hay Fever and Allergic Conjunctivitis (AC). The amount of dosage is contingent upon the approach of delivery (e.g. Solution - Ophthalmic or Spray, metered) as noted in the table below.Condition
Dosage
Administration
Allergic Conjunctivitis (AC)
, 0.6 mg, 2.0 mg/mL, 1.11 mg/mL, 0.665 mg, 1.0 mg/mL, 0.1 %, 0.2 %, 6.65 mg/mL, 7.0 mg/mL, 0.7 %
, Nasal, Spray, metered, Spray, metered - Nasal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Spray, Spray - Nasal, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid
Hay Fever
, 0.6 mg, 2.0 mg/mL, 1.11 mg/mL, 0.665 mg, 1.0 mg/mL, 0.1 %, 0.2 %, 6.65 mg/mL, 7.0 mg/mL, 0.7 %
, Nasal, Spray, metered, Spray, metered - Nasal, Ophthalmic, Solution / drops, Solution / drops - Ophthalmic, Spray, Spray - Nasal, Solution, Solution - Ophthalmic, Liquid - Ophthalmic, Liquid
Warnings
Patanase has four contraindications. Under no circumstances should it be taken in combination with the situations documented in the following table.Patanase ContraindicationsCondition
Risk Level
Notes
Severe Hypersensitivity Reactions
Do Not Combine
Olopatadine may interact with Pulse Frequency
Common Patanase Drug Interactions
Drug Name
Risk Level
Description
Patanase Toxicity & Overdose RiskThe most toxic dose of olopatadine found in mice was 1150 mg/kg, and in rats was 3870 mg/kg. The lowest toxic dose in rats was 20 mg/kg and in mice was 0.1 mg/kg. If someone is suspected to have overdosed on olopatadine, the symptoms may range from agitation and restlessness to drowsiness in adults and children. Treatment for olopatadine overdose should be supportive and symptomatic.
Patanase Novel Uses: Which Conditions Have a Clinical Trial Featuring Patanase?
Nine active clinical trials are being conducted to ascertain the potential of Patanase in ameliorating Hay Fever, Allergic Rhinitis and Allergic Conjunctivitis (AC).Condition
Clinical Trials
Trial Phases
Hay Fever
0 Actively Recruiting
Allergic Conjunctivitis (AC)
1 Actively Recruiting
Phase 2
Patanase Reviews: What are patients saying about Patanase?
5Patient Review
2/6/2016 This is the best allergy/sinus spray I've ever used, and believe me, I've tried everything over the years. The real key to making it work though is using a Nelimed nose cleaner with a 0.5mg Budesonide solution first. It clears out your sinuses so that the spray can do its job more effectively.
5Patient Review
9/11/2013 Be sure to keep your head down when using this spray, otherwise you'll taste it in the back of your throat. Also, I found that waiting a minute or two between sprays helped minimize the taste.
5Patient Review
2/9/2018 This medication is extremely effective. A tip: make sure to follow the directions and sniff when you spray it in your nose so that it doesn't end up in your mouth.
5Patient Review
8/20/20115Patient Review
11/18/2011 My four year old daughter suddenly developed hives all over her chest and back.
5Patient Review
9/11/2012 The taste is unpleasant, but this is an extremely effective treatment when other options have failed.
5Patient Review
11/9/2013 This is the best treatment I've ever tried.
3Patient Review
11/6/2011 This medication is the only thing that has worked for me. I find that taking it in combination with Patanase is ideal. Patanase can be pricey, but it is well worth it in my opinion.
3Patient Review
3/29/2016 The doctor said to spray this twice in each nostril, but that seems like a lot. especially because it always drains into my throat/mouth with a really bitter taste. I don't know if it's effective yet because I've only been using it for four days.
3Patient Review
6/13/2012 I wasn't sure if I would like using a nose spray, but this one is really fine and it's helped me a lot.
Patient Q&A Section about patanase
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.Is Patanase nasal spray a steroid?
"Patanase will be available by the end of May and will offer relief beginning in minutes according to Alcon."
Answered by AI
Is there a generic for Patanase?
"This medicine helps relieve itching, running, and stuffiness in the nose caused by allergies and other irritants."
Answered by AI
What is Patanase nasal spray used for?
"This medication is an antihistamine used to relieve symptoms of seasonal allergies that occur in the nose, such as runny/itchy/stuffy nose, sneezing, and post-nasal drip."
Answered by AI
Is Patanase nasal spray over the counter?
"Patanase Nasal Spray is a medication prescribed by doctors to treat the symptoms of allergies that occur during specific seasons. The spray can be used by itself or with other medications."
Answered by AI