Biguanide
Metformin for Prediabetes
Recruiting2 awardsPhase 4
Phoenix, Arizona
This trial is testing whether metformin can lower the risk of death, heart attacks, and strokes in people with pre-diabetes and heart or blood vessel issues. Metformin is a drug that helps control blood sugar levels and has been used to treat type 2 diabetes mellitus for more than 60 years. The study involves patients who have pre-diabetes and existing heart or blood vessel problems, aiming to see if metformin can provide additional health benefits.
Behavioural Intervention
Lifestyle Intervention for Preventing Type 2 Diabetes
Recruiting1 award2 criteria
Salt Lake City, Utah
This trial aims to study a new program to prevent type 2 diabetes in adults in the US. The program focuses on lifestyle changes and support from romantic partners to create long-lasting effects.
Behavioral Intervention
Heat Therapy for Prediabetes
Recruiting0 awards4 criteria
Lubbock, Texas
This trial aims to determine if using heat pads on the legs can improve muscle health, physical function, and blood sugar control in older individuals with prediabetes as effectively as High-Intensity Interval Training (
Hormone Therapy
Insulin Management for Non-alcoholic Fatty Liver Disease
Recruiting1 awardPhase 1
New York, New York
"This trial aims to study the effects of lowering insulin levels on liver glucose production and fat synthesis in individuals with insulin resistance and fatty liver disease. Participants will undergo two procedures with different insulin levels to compare the
Behavioural Intervention
Exercise Training for Aging
Recruiting1 award
Durham, North Carolina
This trial aims to investigate how aging affects physical fitness and resilience in older adults who have previously completed an exercise program. The study will involve up to 8 participants who will take part in a 6
Behavioural Intervention
Time-Restricted Eating for Type 2 Diabetes
Recruiting1 award4 criteria
Toronto, Ontario
This trial studies the effects of timing of eating on blood sugar in those with obesity and type 2 diabetes. Participants are assigned a 4-12hr eating window with no restrictions on the food they eat. Results will compare 3 9hr windows to determine if start and stop time impacts blood sugar.
Popular Filters
Trials for Incretin Hormones In Polycystic Ovary Syndrome Patients
Behavioral Intervention
Small Steps for Big Changes Program for Prediabetes
Recruiting1 award4 criteria
Kelowna, British Columbia
This trial evaluates the effectiveness of the 'Small Steps for Big Changes' (SSBC) program, designed to help people with prediabetes improve their diet and exercise habits. The goal is to see if these changes can lower blood sugar levels, reduce weight, and decrease waist size over time. Participants receive personalized guidance and support from trainers at YMCA locations. The 'Small Steps for Big Changes' (SSBC) program emphasizes behavior change techniques and motivational interviewing to help adults at risk for type 2 diabetes.
Potassium Channel Activator
Diazoxide for Non-alcoholic Fatty Liver Disease
Recruiting0 awardsPhase 1
New York, New York
This trial will compare 2 doses of diazoxide to placebo to see how they affect glucose and fat metabolism in people with IR-NAFLD. Participants will take 27 doses, have fasting blood tests and wear a glucose monitor for 14 days.
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Empagliflozin for Prediabetes
Recruiting2 awardsPhase 4
Corvallis, Oregon
This trial is testing whether the drug empagliflozin can help improve regulation of blood sugar in overweight or obese adults with prediabetes. They will also be looking at possible mechanisms to explain how empagliflozin might improve metabolism in skeletal muscle.
Trials for Prediabetes Patients
Behavioral Intervention
Small Steps for Big Changes Program for Prediabetes
Recruiting1 award4 criteria
Kelowna, British Columbia
This trial evaluates the effectiveness of the 'Small Steps for Big Changes' (SSBC) program, designed to help people with prediabetes improve their diet and exercise habits. The goal is to see if these changes can lower blood sugar levels, reduce weight, and decrease waist size over time. Participants receive personalized guidance and support from trainers at YMCA locations. The 'Small Steps for Big Changes' (SSBC) program emphasizes behavior change techniques and motivational interviewing to help adults at risk for type 2 diabetes.
Potassium Channel Activator
Diazoxide for Non-alcoholic Fatty Liver Disease
Recruiting0 awardsPhase 1
New York, New York
This trial will compare 2 doses of diazoxide to placebo to see how they affect glucose and fat metabolism in people with IR-NAFLD. Participants will take 27 doses, have fasting blood tests and wear a glucose monitor for 14 days.
Sodium-glucose cotransporter 2 (SGLT2) inhibitor
Empagliflozin for Prediabetes
Recruiting2 awardsPhase 4
Corvallis, Oregon
This trial is testing whether the drug empagliflozin can help improve regulation of blood sugar in overweight or obese adults with prediabetes. They will also be looking at possible mechanisms to explain how empagliflozin might improve metabolism in skeletal muscle.
Trials With No Placebo
Behavioral Intervention
Small Steps for Big Changes Program for Prediabetes
Recruiting1 award4 criteria
Kelowna, British Columbia
This trial evaluates the effectiveness of the 'Small Steps for Big Changes' (SSBC) program, designed to help people with prediabetes improve their diet and exercise habits. The goal is to see if these changes can lower blood sugar levels, reduce weight, and decrease waist size over time. Participants receive personalized guidance and support from trainers at YMCA locations. The 'Small Steps for Big Changes' (SSBC) program emphasizes behavior change techniques and motivational interviewing to help adults at risk for type 2 diabetes.
Behavioral Intervention
Exercise Training for Fat Metabolism in Postmenopausal Women
Recruiting1 award1 criteria
Tallahassee, Florida
This trial will study how well resistance training improves fat metabolism in postmenopausal women with obesity and pre-diabetes, to see if it could help prevent type 2 diabetes.
Behavioral Intervention
Quality Improvement and Implementation Science for Mental and Physical Health in Women Veterans
Recruiting1 award1 criteria
West Los Angeles, California
This trial is testing two strategies to help support and sustain evidence-based practices for women Veterans in up to 20 VA facilities.
Frequently Asked Questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the 'trial drug' — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
Is there any support for travel costs?
Many of the teams running clinical trials will cover the cost of transportation to-and-from their care center.
Will I know what medication I am taking?
This depends on the specific study. If you're worried about receiving a placebo, you can actively filter out these trials using our search.
How long do clinical trials last?
Some trials will only require a single visit, while others will continue until your disease returns. It's fairly common for a trial to last somewhere between 1 and 6 months.
Do you verify all the trials on your website?
All of the trials listed on Power have been formally registered with the US Food and Drug Administration. Beyond this, some trials on Power have been formally 'verified' if the team behind the trial has completed an additional level of verification with our team.
How quickly will I hear back from a clinical trial?
Sadly, this response time can take anywhere from 6 hours to 2 weeks. We're working hard to speed up how quickly you hear back — in general, verified trials respond to patients within a few days.