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Amnion Wound Covering for Enhanced Wound Healing

Phase < 1
Waitlist Available
Led By Joseph Molnar, MD, PhD
Research Sponsored by Wake Forest University Health Sciences
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 26 weeks
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a special powder made from the placenta to see if it can help wounds heal better. It targets patients with skin graft wounds, aiming to provide a faster and more complete healing process by acting as a protective covering and promoting new skin growth. Human placental extracts are known to help wound healing.

Eligible Conditions
  • Cuts
  • Burns
  • Dermabrasion

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 26 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 26 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Incidence of Donor Site Wound Closure
Secondary study objectives
Injury wounds
Dermatitis
Presence of infection
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Amnion membrane product treatment areaExperimental Treatment2 Interventions
The prepared amnion membrane powder will be directly applied to the prepared donor wound site (Site A). The wound will then be covered with the SOC dressing.
Group II: SOC Wound Covering treatment areaActive Control1 Intervention
The donor wound site (Site B) will be covered per SOC (Standard of care).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Amnion Membrane Powder
2019
Completed Early Phase 1
~10
SOC Wound Covering
2019
Completed Early Phase 1
~10

Find a Location

Who is running the clinical trial?

Wake Forest University Health SciencesLead Sponsor
1,397 Previous Clinical Trials
2,460,123 Total Patients Enrolled
Joseph Molnar, MD, PhDPrincipal InvestigatorWake Forest University Health Sciences
2 Previous Clinical Trials
11 Total Patients Enrolled

Media Library

SOC Wound Covering (Other) Clinical Trial Eligibility Overview. Trial Name: NCT03754218 — Phase < 1
Burns Research Study Groups: Amnion membrane product treatment area, SOC Wound Covering treatment area
Burns Clinical Trial 2023: SOC Wound Covering Highlights & Side Effects. Trial Name: NCT03754218 — Phase < 1
SOC Wound Covering (Other) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03754218 — Phase < 1
~1 spots leftby Dec 2025