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Retinoid

Acne Subjects on Systemic Isotretinoin Treatment for Acne

Phase < 1
Waitlist Available
Research Sponsored by University of California, Davis
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Summary

There are two purposes of this study: 1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne. 2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Trial Design

3Treatment groups
Experimental Treatment
Active Control
Group I: Acne Subjects on Topical Tretinoin TreatmentExperimental Treatment1 Intervention
Subjects with acne before and after topical retinoid therapy
Group II: Acne Subjects on Systemic Isotretinoin TreatmentExperimental Treatment1 Intervention
Subjects with acne before and after isotretinoin therapy
Group III: No AcneActive Control1 Intervention
Healthy subjects without acne between the ages of 15-45
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Isotretinoin
FDA approved
Tretinoin
FDA approved

Find a Location

Who is running the clinical trial?

University of California, DavisLead Sponsor
932 Previous Clinical Trials
4,721,311 Total Patients Enrolled
4 Trials studying Acne
376 Patients Enrolled for Acne
~3 spots leftby Sep 2025
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