Local Multimodal Analgesia vs Regional Anesthesia for Ankle Fracture

Recruiting in Palo Alto (17 mi)

+1 other location

Overseen byJustin Haller, MD

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase < 1

Waitlist Available

Sponsor: University of Utah

No Placebo Group

Trial Summary

What is the purpose of this trial?The investigators plan to evaluate the efficacy in reducing post-operative pain between local multimodal analgesia as compared to regional anesthesia in rotational ankle fractures.

Eligibility Criteria

This trial is for individuals with isolated rotational ankle fractures who need surgery, can give informed consent, and communicate in English or Spanish. It's not for those with drug dependency history, stroke, major neurological issues, other leg fractures, allergies to injection ingredients used in the study, head injuries or open fractures.

Inclusion Criteria

I need surgery for a broken ankle caused by twisting it.

Ability to provide informed consent

I can talk or email the research team.

+1 more

Exclusion Criteria

I have a head injury along with my current condition.

Prior drug dependency

Allergies to any of the ingredients in the local injection or peripheral nerve block

+4 more

Participant Groups

The study compares two pain control methods after ankle fracture surgery: one group receives local multimodal analgesia injections at the injury site; another gets regional anesthesia that numbs a larger area of the body.

2Treatment groups

Experimental Treatment

Active Control

Group I: Local multimodal analgesia groupExperimental Treatment1 Intervention

Local multimodal analgesia composition will include 5mg of morphine, 500 mg of epinephrine, 15mg of ketorolac, and 20mg of bupivacaine.

Group II: Regional anesthesia groupActive Control1 Intervention

Standard single-shot anesthesia consists of bupivacaine 0.25% with epinephrine 1:400,000.