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Behavioral Intervention
Light Therapy for Obsessive-Compulsive Disorder (KLTO Trial)
Phase < 1
Recruiting
Led By Rebecca Cox, PhD
Research Sponsored by Washington University School of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Primary DSM-5 OCD diagnosis
Age 18-35
Timeline
Screening 3 weeks
Treatment Varies
Follow Up administered 4 times/day for 2 weeks at baseline, 4 times/day for 1 week in treatment week 3, and 4 times/day for 1 week in treatment week 5
Summary
This trial aims to see if light therapy can help young adults with OCD and late bedtimes. They want to know if light therapy can reduce OCD symptoms and help regulate the body's internal clock. Some
Who is the study for?
This trial is for young adults with Obsessive-Compulsive Disorder (OCD) who typically go to bed at 1am or later. Participants will use light therapy glasses and track their sleep, while also completing assessments related to their OCD symptoms.
What is being tested?
The study tests if light therapy can reduce OCD symptoms and adjust the body's internal clock. It may compare different doses of light therapy to see if a higher dose is more effective than a lower one.
What are the potential side effects?
Potential side effects are not detailed in the provided information, but common ones for light therapy could include eye strain, headache, nausea, irritability or agitation.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have been diagnosed with OCD.
Select...
I am between 18 and 35 years old.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ administered 4 times/day for 2 weeks at baseline, 4 times/day for 1 week in treatment week 3, and 4 times/day for 1 week in treatment week 5
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~administered 4 times/day for 2 weeks at baseline, 4 times/day for 1 week in treatment week 3, and 4 times/day for 1 week in treatment week 5
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Primary study objectives
Daily Perseverative Thinking Questionnaire
Yale Brown Obsessive-Compulsive Scale (YBOCS)
Secondary study objectives
Circadian melatonin phase
Trial Design
2Treatment groups
Experimental Treatment
Placebo Group
Group I: Higher doseExperimental Treatment1 Intervention
Participants will be given wearable light therapy devices that emit a higher light intensity.
Group II: Lower dosePlacebo Group1 Intervention
Participants will be given wearable light therapy devices that emit a lower light intensity.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Light therapy
2004
N/A
~370
Find a Location
Who is running the clinical trial?
Washington University School of MedicineLead Sponsor
1,999 Previous Clinical Trials
2,335,448 Total Patients Enrolled
1 Trials studying Obsessive-Compulsive Disorder
61 Patients Enrolled for Obsessive-Compulsive Disorder
Rebecca Cox, PhDPrincipal InvestigatorWashington University School of Medicine
1 Previous Clinical Trials
3,800 Total Patients Enrolled