Computerized Cognitive Training for Psychosis (Rem-STEP Trial)

Phase < 1

Recruiting

Led By Caroline Demro, PhD

Research Sponsored by University of Minnesota

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, one month follow-up post-intervention

Awards & highlights

No Placebo-Only Group

Summary

This trial will study state representation in young adults with and without a psychiatric diagnosis. The trial will involve some observational tests and a cognitive training clinical trial.

Who is the study for?

This trial is for individuals aged 18-45 with conditions like schizophrenia or mood disorders with psychotic features, fluent in English, and have been stable outside a hospital for at least a month. They must not have severe substance use recently, significant cognitive training experience within the last six months, or other neurological disorders (except autism).

What is being tested?

The study tests two types of computerized cognitive training designed to improve information processing about surroundings in young adults with psychosis compared to those without psychiatric diagnoses.

What are the potential side effects?

Since this trial involves non-invasive computerized cognitive training exercises, there are no direct physical side effects expected from participating. However, participants may experience mental fatigue or stress.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, one month follow-up post-intervention

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, one month follow-up post-intervention

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, one month follow-up post-intervention for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Change in Performance of Bandit Task Variant

Change in Performance of DPX Task Variant

Secondary study objectives

Brain

Change in Test My Brain Neurocognitive Assessment performance: Matrix Reasoning Z Score

Change in Test My Brain Neurocognitive Assessment performance: Multiracial Emotion Identification Z Score

+2 more

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups

Experimental Treatment

Group I: Visual Perception TrainingExperimental Treatment1 Intervention

Contains targeted visual perception exercises from BrainHQ's suite of cognitive exercises. This training paradigm is designed to improve state estimation processes at the perceptual input level.

Group II: Visual Cognitive Control TrainingExperimental Treatment1 Intervention

Contains targeted visual cognitive control exercises from BrainHQ's suite of exercises. This training paradigm is designed to enhance state representation stability of visual information.

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