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A Study to Assess the Safety, Tolerability and Drug Levels of BMS-986172 in Healthy and Obese Participants, Including an Assessment of the Effects of Food on BMS-986172 Absorption

Phase 1
Waitlist Available
Research Sponsored by Bristol-Myers Squibb
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 28 days

Summary

This trial is testing a new drug called BMS-986172 to see if it is safe, how well people tolerate it, and how food affects its absorption. The study likely involves healthy volunteers or a general population.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 28 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 28 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Incidence of clinically significant changes in ECG parameters: QTcF

Trial Design

4Treatment groups
Experimental Treatment
Group I: Part D: FE/BAExperimental Treatment1 Intervention
FE/BA = Food Effect/Relative Bioavailability
Group II: Part C: JMADExperimental Treatment2 Interventions
JMAD= Japanese Multiple Ascending Dose
Group III: Part B: MADExperimental Treatment2 Interventions
MAD = Multiple Ascending Dose
Group IV: Part A: SADExperimental Treatment2 Interventions
SAD = Single Ascending Dose
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
BMS-986172
2021
Completed Phase 1
~40

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Bristol-Myers SquibbLead Sponsor
2,696 Previous Clinical Trials
4,099,031 Total Patients Enrolled
~9 spots leftby Dec 2025