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AMG 890 for Cardiovascular Disease

Phase 1
Waitlist Available
Research Sponsored by Amgen
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 365 days

Summary

This trial tests a new drug called AMG 890 in people with high levels of Lipoprotein(a), which is linked to heart disease. The study will check if the drug is safe and how well people tolerate it. Researchers will also see how the drug moves through the body and its effect on Lipoprotein(a) levels. AMG 890 is currently being tested for its effectiveness in reducing lipoprotein(a) levels.

Eligible Conditions
  • Cardiovascular Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 365 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 365 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Changes in PR interval
Changes in QRS interval
Changes in QT interval
+15 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: AMG 890Experimental Treatment1 Intervention
Single Ascending Dose Cohorts
Group II: PlaceboPlacebo Group1 Intervention
Single Ascending Dose Cohorts
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
AMG 890
2018
Completed Phase 1
~80

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

AmgenLead Sponsor
1,433 Previous Clinical Trials
1,395,063 Total Patients Enrolled
MDStudy DirectorAmgen
971 Previous Clinical Trials
939,235 Total Patients Enrolled
~11 spots leftby Nov 2025
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