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Corticosteroid

Mometasone 1mg for Chronic Sinusitis

Phase 1
Waitlist Available
Led By Bobby Tajudeen, MD
Research Sponsored by Rush University Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up morning (am) at week 12,
Awards & highlights
No Placebo-Only Group

Summary

This trial tests different doses of mometasone in nasal irrigation for patients with chronic sinusitis. The goal is to see if it affects cortisol levels in the body. Mometasone helps reduce nasal inflammation and is less likely to enter the bloodstream, making it safer for long-term use. Mometasone furoate has been used in various forms, such as nasal sprays and gels, to treat sinusitis and reduce nasal inflammation.

Eligible Conditions
  • Chronic Sinusitis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~morning (am) at week 12,
This trial's timeline: 3 weeks for screening, Varies for treatment, and morning (am) at week 12, for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Morning "AM" Serum Cortisol Level

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

3Treatment groups
Experimental Treatment
Group I: Mometasone 4mgExperimental Treatment1 Intervention
4mg capsule dissolved in 240mg saline solution nasal irrigation
Group II: Mometasone 2mgExperimental Treatment1 Intervention
2mg capsule dissolved in 240mg saline solution nasal irrigation
Group III: Mometasone 1mgExperimental Treatment1 Intervention
1mg capsule dissolved in 240mg saline solution nasal irrigation
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Mometasone
Not yet FDA approved

Find a Location

Who is running the clinical trial?

Rush University Medical CenterLead Sponsor
435 Previous Clinical Trials
249,278 Total Patients Enrolled
Advanced RxIndustry Sponsor
Bobby Tajudeen, MDPrincipal InvestigatorRush University Medical Center
~2 spots leftby Nov 2025
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