Your session is about to expire
← Back to Search
Other
Combination Drug Therapy for Glioblastoma
Phase 1
Waitlist Available
Led By Charles Cobbs, MD
Research Sponsored by Swedish Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights
Study Summary
This trial is testing a new combination drug therapy for people with brain cancer that has come back or gotten worse after other treatments.
Eligible Conditions
- Glioblastoma
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ 1 year
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Overall response rate
Overall survival
Progression free survival
+1 moreTrial Design
1Treatment groups
Experimental Treatment
Group I: Treatment ArmExperimental Treatment1 Intervention
A Drug Combination Treatment will be determined through High Throughput Screening. The classes of drugs this combination therapy will be comprised from are:
Antineoplastic Anti-infective Antiemetic Antihyperlipidemic Anti-inflammatory Antihistamine Antihypertensive Antidepressant Cardiotonic Alcohol antagonist Diuretic Antipsychotic NMDA receptor antagonist Antidiabetic Immunosuppressant Anticonvulsant Antimethemoglobinemic Sclerosing agent
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Combination Drug Therapy
2015
Completed Phase 1
~10
Find a Location
Who is running the clinical trial?
Swedish Medical CenterLead Sponsor
54 Previous Clinical Trials
8,485 Total Patients Enrolled
1 Trials studying Glioblastoma
10 Patients Enrolled for Glioblastoma
Charles Cobbs, MDPrincipal InvestigatorSwedish Medical Center
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- You have experienced dangerous episodes of high blood pressure in the past.You had a heart attack or unstable chest pain in the last 6 months.You have received chemotherapy treatment within the past 4 weeks.You have taken procarbazine within the past 3 weeks.You have had a hole or tear in your stomach or intestines within the past 6 months.You have allergies to the substances used in this study.You are currently taking herbal medications.You have a severe wound, ulcer, or broken bone that is not healing or being treated.You had a stroke or mini-stroke (TIA) within the past 6 months.Your disease has gotten worse after receiving radiation therapy and TMZ treatment. You can have multiple relapses, as long as you still meet the other requirements for joining the study.You have taken nitrosoureas within the past 6 weeks.You have a medical condition that could make it difficult to determine if the treatment is working or if it could affect how your body processes the drug in a dangerous way.You have moderate to severe heart failure according to the New York Heart Association classification.You have had a significant amount of bright red blood when coughing within the past month.You have recently had a major blood vessel problem, like an aneurysm or a blockage in your arms or legs.This assessment will be done when the tumor comes back and after you finish your previous treatment.
Research Study Groups:
This trial has the following groups:- Group 1: Treatment Arm
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger