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Topical Agent

PF-07295324 for Healthy Subjects

Phase 1
Waitlist Available
Research Sponsored by Pfizer
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up on days 1, 2, 5, 7, 10, 11, 12, and early termination (if applicable) at pre-dose, 1, 2, 4, 6, 8, 12, and 24 hours after application
Awards & highlights
No Placebo-Only Group

Summary

This trial tests two skin creams on healthy adults to see if they are safe and how they are absorbed by the body.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~on days 1 and 10 at pre-dose, 1, 2, 4, 6, 8, 12, and 24 hours after application
This trial's timeline: 3 weeks for screening, Varies for treatment, and on days 1 and 10 at pre-dose, 1, 2, 4, 6, 8, 12, and 24 hours after application for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Number of Participants With Adverse Events (AEs) and Serious Adverse Events (SAEs)
Number of Participants With Clinically Significant Abnormalities in Electrocardiogram (ECG) Findings
Number of Participants With Laboratory Abnormalities
+2 more
Secondary study objectives
AUCtau of PF-07259955 on Days 1 and 10
Apparent Clearance (CL/F) of PF-07295324 on Day 10
Apparent Volume of Distribution (Vz/F) of PF-07295324 on Day 10
+17 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: PF-07295324Experimental Treatment1 Intervention
Ointment
Group II: PF-07259955Experimental Treatment1 Intervention
Cream
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
PF-07295324
2022
Completed Phase 1
~30
PF-07259955
2022
Completed Phase 1
~30

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

PfizerLead Sponsor
4,658 Previous Clinical Trials
17,877,263 Total Patients Enrolled
Pfizer CT.gov Call CenterStudy DirectorPfizer
3,544 Previous Clinical Trials
14,918,439 Total Patients Enrolled
~6 spots leftby Nov 2025
Unbiased ResultsWe believe in providing patients with all the options.
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