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Low bicarbonate dialysis for Chronic Kidney Disease

Phase 1
Waitlist Available
Led By Matthew K Abramowitz, MD, MS
Research Sponsored by Albert Einstein College of Medicine
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1-2 weeks
Awards & highlights
No Placebo-Only Group

Summary

This study will compare acid-base changes during hemodialysis treatments with a standard dialysis bath versus a lower bicarbonate dialysis bath, and aims to define the factors that limit equilibration of the bicarbonate concentration in a patient's blood with that in the dialysate.

Eligible Conditions
  • Acidosis
  • Chronic Kidney Disease

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1-2 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1-2 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in beta-hydroxybutyrate clearance
Change in lactate clearance

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Low bicarbonate dialysisExperimental Treatment1 Intervention

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Who is running the clinical trial?

Albert Einstein College of MedicineLead Sponsor
296 Previous Clinical Trials
11,688,887 Total Patients Enrolled
Matthew K Abramowitz, MD, MSPrincipal InvestigatorAlbert Einstein College of Medicine
~1 spots leftby Dec 2025
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