Alcohol + THC for DUI Effects
(THC-ETOH-I Trial)

Recruiting in Palo Alto (17 mi)

Age: 18 - 65

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 1

Waitlist Available

Sponsor: Yale University

Trial Summary

What is the purpose of this trial?The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.

Eligibility Criteria

This trial is for occasional cannabis users aged 21-55 who have drunk alcohol at least once. They must understand the study and agree to participate. People can't join if they've never used cannabis or alcohol, have hearing problems, or are pregnant.

Inclusion Criteria

Occasional current cannabis users

I am between 21 and 55 years old.

Experience with drinking 2 or more standard drinks of alcohol at least once in lifetime

+1 more

Exclusion Criteria

Cannabis naïve

Alcohol naïve

Positive pregnancy screen

+1 more

Participant Groups

The study aims to understand how ethanol (found in alcoholic drinks) and delta-9-THC (from cannabis) affect simulated driving and thinking skills. Participants will either receive active oral ethanol, a placebo, or inhale active THC.

4Treatment groups

Experimental Treatment

Placebo Group

Group I: Placebo THC and Active EthanolExperimental Treatment2 Interventions

Group II: Active THC and Placebo EthanolExperimental Treatment2 Interventions

Group III: Active THC and Active EthanolExperimental Treatment2 Interventions

Group IV: Placebo THC and Placebo EthanolPlacebo Group1 Intervention