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Exercise for Stable Myasthenia Gravis

Phase 1
Waitlist Available
Led By Charlene E Hafer-Macko, MD
Research Sponsored by Baltimore VA Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
No Placebo-Only Group

Summary

Generalized fatigue in myasthenia gravis results in physical deconditioning that reduces fitness and increases risk of obesity, hypertension, elevated cholesterol and type 2 diabetes. This study will examine how active and fit are 30 individuals with chronic, generalized myasthenic subjects. This study will also determine whether a 3 month home exercise program with aerobic, resistive, and pulmonary training can improve physical activity, strength, fitness, lung function and reduce cardiovascular disease risk.

Eligible Conditions
  • Myasthenia Gravis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: exerciseExperimental Treatment1 Intervention
Multimodal exercises that include walking, breathing exercises, dynamic balance, and core strengthening.

Find a Location

Who is running the clinical trial?

Baltimore VA Medical CenterLead Sponsor
32 Previous Clinical Trials
3,065 Total Patients Enrolled
University of MarylandOTHER
169 Previous Clinical Trials
306,911 Total Patients Enrolled
Charlene E Hafer-Macko, MDPrincipal InvestigatorBaltimore VA Medical Center
~2 spots leftby Dec 2025