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Legume

Pea Muffins for Blood Sugar and Appetite Control (PEA3 Trial)

N/A
Waitlist Available
Led By Heather Blewett, PhD
Research Sponsored by St. Boniface Hospital
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Must not have
Medical history of cardiovascular disease
Medical history of diabetes mellitus, fasting blood glucose ≥6.1 mmol/L, HbA1c ≥6.0%, or use of insulin or oral medication to control blood sugar
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 120 min

Summary

This trial is testing the effects of different types of peas on blood sugar and appetite in healthy people.

Who is the study for?
Healthy men and women aged 18-40, with a BMI of 18.5-30, who eat three meals daily can join this study on peas in muffins affecting blood sugar and fullness. Excluded are those with diabetes, abnormal cholesterol or triglycerides, recent major surgery, liver/kidney disease, cancer treatment within a year, shift workers, unstable weight or dieting individuals.
What is being tested?
The trial is testing how different types of muffins (split pea muffins vs wheat muffins vs whole pea muffins) affect post-meal blood sugar levels and feelings of fullness in healthy volunteers as part of research on the physical effects of peas.
What are the potential side effects?
Since the interventions involve eating different types of muffins made from peas or wheat which are common foods, no significant side effects are expected beyond potential mild digestive discomfort for some individuals.

Eligibility Criteria

Exclusion Criteria

You may be eligible for the trial if you check “No” for criteria below:
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I have a history of heart disease.
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I have diabetes or my blood sugar levels are high.
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My liver tests are higher than normal, indicating liver issues.
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My weight has been stable; I haven't lost or gained more than 5% in the last 3 months.
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I have not had major surgery in the last 3 months.
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I am unwilling or unable to eat the foods required for the study.
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I have a history of kidney disease or my kidney tests are not normal.
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I am not taking any medication or supplements that affect blood sugar or appetite.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~120 min
This trial's timeline: 3 weeks for screening, Varies for treatment, and 120 min for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Post-prandial glucose response
Post-prandial insulin
Secondary study objectives
Appetite ratings
Other study objectives
Acceptability of test products
Gastrointestinal side effects
Metabolomics
+1 more

Trial Design

4Treatment groups
Experimental Treatment
Placebo Group
Group I: whole yellow peaExperimental Treatment1 Intervention
2 muffins containing 25g available carbohydrate from whole yellow peas. Intervention: Whole pea muffins
Group II: split yellow peaExperimental Treatment1 Intervention
2 muffins containing 25g available carbohydrate from split yellow peas. Intervention: Split pea muffins
Group III: wheat-satietyPlacebo Group1 Intervention
2 muffins containing wheat flour to match the calories in the whole and split pea muffins. Intervention: Wheat muffins
Group IV: wheat-PPGRPlacebo Group1 Intervention
2 muffins containing 25g available carbohydrate from wheat flour. Intervention: Wheat muffins

Find a Location

Who is running the clinical trial?

University of ManitobaOTHER
619 Previous Clinical Trials
206,697 Total Patients Enrolled
St. Boniface HospitalLead Sponsor
54 Previous Clinical Trials
15,010 Total Patients Enrolled
Agriculture and Agri-Food CanadaOTHER_GOV
34 Previous Clinical Trials
2,293 Total Patients Enrolled
~3 spots leftby Nov 2025
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