~28 spots leftby Apr 2026

Donors After Circulatory Death Heart Trial

Recruiting in Palo Alto (17 mi)
+24 other locations
Age: 18+
Sex: Any
Travel: May Be Covered
Time Reimbursement: Varies
Trial Phase: Academic
Waitlist Available
Sponsor: TransMedics
No Placebo Group

Trial Summary

What is the purpose of this trial?

To evaluate the effectiveness of the OCS Heart System to resuscitate, preserve and assess hearts donated after circulatory death for transplantation to increase the pool of donor hearts available for transplantation.

Research Team

Eligibility Criteria

Inclusion Criteria

Donor Inclusion
Maastricht Category III DCD donor, defined as expected death after the withdrawal of life- supportive therapy (WLST)
Donor age 18-49 years old inclusive
See 7 more

Treatment Details

Interventions

  • Cold Storage (Procedure)
  • OCS Heart System (Organ Preservation Device)
Participant Groups
2Treatment groups
Experimental Treatment
Active Control
Group I: DCD Heart PossibleExperimental Treatment1 Intervention
Group II: Standard of Care Heart OnlyActive Control1 Intervention

Find a Clinic Near You

Research Locations NearbySelect from list below to view details:
University of MinnesotaMinneapolis, MN
Yale New Haven HospitalNew Haven, CT
University of California San DiagoLa Jolla, CA
Cedars SinaiLos Angeles, CA
More Trial Locations
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Who Is Running the Clinical Trial?

TransMedics

Lead Sponsor

Trials
24
Patients Recruited
213,000+