← Back to Search

Dietary Supplement

Choline for Cardiovascular Risk

N/A
Waitlist Available
Led By Kevin Davy, PhD
Research Sponsored by Virginia Polytechnic Institute and State University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10
Awards & highlights

Study Summary

This trial is looking at whether a metabolite produced by gut microbes, Trimethylamine-N-oxide (TMAO), is linked to increased risk of cardiovascular disease in humans. They will be supplementing participants with dietary choline to see if it has any effect on cardiovascular disease risk factors.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10
This trial's timeline: 3 weeks for screening, Varies for treatment, and 3-hour test in laboratory at 4 timepoints; baseline, week 4, week 6, and week 10 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in Insulin Sensitivity after Supplementation
Secondary outcome measures
Glucose

Trial Design

2Treatment groups
Active Control
Placebo Group
Group I: Choline supplementationActive Control1 Intervention
Participants will consume 1000 mg of choline per day for 4 weeks.
Group II: Placebo supplementationPlacebo Group1 Intervention
Participants will consume 1000 mg of placebo per day for 4 weeks.

Find a Location

Who is running the clinical trial?

Virginia Polytechnic Institute and State UniversityLead Sponsor
144 Previous Clinical Trials
27,813 Total Patients Enrolled
3 Trials studying Cardiovascular Risk
60 Patients Enrolled for Cardiovascular Risk
Kevin Davy, PhDPrincipal Investigator - Virginia Polytechnic Institute & State University
Virginia Polytechnic Institute and State University
4 Previous Clinical Trials
102 Total Patients Enrolled
3 Trials studying Cardiovascular Risk
60 Patients Enrolled for Cardiovascular Risk
~4 spots leftby Jun 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top