Automated MR-Guided Radiation for Breast Cancer

Recruiting in Palo Alto (17 mi)

Overseen byRobert Dinniwell, M.D.

Age: 18+

Sex: Female

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Academic

Waitlist Available

Sponsor: University Health Network, Toronto

No Placebo Group

Trial Summary

What is the purpose of this trial?In the proposed research study, we are investigating the feasibility of integrating automated planning tools to MR images acquired using a novel MR-guided linac, for on-line adaptive radiation treatment. However, these on-line automation tools require further technical refinement and clinical validation. The goal of this research proposal is to develop an on-line MR-guided radiation therapy process for adapting breast IMRT treatment. Such an approach will provide early stage breast cancer patients timely access to high-quality adaptive treatments without exposure to additional ionizing radiation.

Eligibility Criteria

This trial is for female patients over 18 with any stage of breast cancer, who will undergo standard whole breast radiation therapy. It's open to those who've had surgery or chemotherapy for any cancer type and can consent in writing.

Inclusion Criteria

I have had surgery or chemotherapy for cancer before.

Able to provide a written informed consent

I will receive standard breast radiation therapy in one of the specified dose plans.

+2 more

Exclusion Criteria

I am male.

I received lower than the standard dose of radiation for my breast.

I am unable to understand and give consent for my treatment.

+2 more

Participant Groups

The study tests an automated planning tool that uses MR images from a new MR-guided linac for on-line adaptive radiation treatment, aiming to refine this technology and validate its clinical use without extra ionizing radiation.

1Treatment groups

Experimental Treatment

Group I: IMRT + CT + MR scanExperimental Treatment1 Intervention