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Age-associated Arterial Dysfunction, Western Diet, and Aerobic Exercise: Role of the Gut Microbiome

N/A
Waitlist Available
Led By Douglas R Seals, PhD
Research Sponsored by University of Colorado, Boulder
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 days
Awards & highlights
No Placebo-Only Group

Summary

This trial will study how different diets and levels of exercise affect the gut microbiome and the function of arteries.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Change in arterial stiffness
Change in endothelial function
Change in the gut microbiome

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Western diet firstExperimental Treatment2 Interventions
To receive Western diet controlled feeding first, followed by non-Western diet controlled feeding
Group II: Non-Western diet firstExperimental Treatment2 Interventions
To receive non-Western diet controlled feeding first, followed by Western diet controlled feeding

Find a Location

Who is running the clinical trial?

University of Colorado, BoulderLead Sponsor
124 Previous Clinical Trials
29,295 Total Patients Enrolled
10 Trials studying Aging
944 Patients Enrolled for Aging
University of California, San DiegoOTHER
1,188 Previous Clinical Trials
1,576,753 Total Patients Enrolled
4 Trials studying Aging
297 Patients Enrolled for Aging
Douglas R Seals, PhDPrincipal InvestigatorUniversity of Colorado, Boulder
7 Previous Clinical Trials
543 Total Patients Enrolled
5 Trials studying Aging
384 Patients Enrolled for Aging
~15 spots leftby Dec 2025