What side effects are associated with this type of intervention?

Treatments targeting the 9 Hallmarks of Aging, such as those in the Cel System protocol, often include a combination of lifestyle changes, dietary supplements, and topical formulations. Common side effects of these treatments can vary but may include mild skin reactions like erythema, pain, or bruising from topical applications. Systemic treatments, such as dietary supplements, may occasionally cause gastrointestinal discomfort or allergic reactions. It is important to monitor for any adverse effects and consult with a healthcare provider to ensure the treatments are appropriate and safe.

What prior FDA approvals exist?

Currently, there are no FDA-approved drugs specifically targeting the 9 Hallmarks of Aging as described in the Cel System protocol. However, various treatments and interventions have been approved that indirectly support healthy aging. These include medications for chronic conditions commonly associated with aging, such as cardiovascular drugs, diabetes medications, and osteoporosis treatments. Additionally, lifestyle interventions like exercise and dietary modifications are widely recommended to promote healthy aging. Research is ongoing to develop targeted therapies that address the biological mechanisms of aging.

What other types of research exist?

Promising novel alternatives to the Cel System protocol for promoting healthy aging include: 1) Senolytics, which target and eliminate senescent cells to reduce inflammation and improve tissue function. 2) NAD+ boosters, such as nicotinamide riboside and nicotinamide mononucleotide, which enhance cellular energy metabolism and repair. 3) mTOR inhibitors like rapamycin, which have been shown to extend lifespan and improve healthspan by modulating cellular growth and metabolism. 4) Epigenetic reprogramming therapies, which aim to reset the epigenetic markers of aging cells to a more youthful state. 5) Advanced glycation end-product (AGE) breakers, which reduce the accumulation of harmful protein cross-links that impair tissue function.

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Dietary Supplement

SRW Cel System for Healthy Aging

Phase 2

Waitlist Available

Research Sponsored by TruDiagnostic

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up change in epigenetic age from baseline to 12 months

Awards & highlights

No Placebo-Only Group

Summary

This trial tests the Cel System protocol, which includes three formulas and an app for healthy lifestyle changes, on people interested in healthy aging. It aims to see how well this combination can affect biological aging markers and overall health.

Who is the study for?

This trial is for individuals aged 55 or older who are post-menopausal (if female), can follow the treatment plan, and have a smartphone to use an app. They must be able to read and speak English, consume supplements during the study, and not have any major health issues that could affect participation.

What is being tested?

The SRW Cel System protocol targets all nine hallmarks of aging with three formulas combined with a lifestyle app. The goal is to see if this approach supports healthy aging by impacting these key biological factors.

What are the potential side effects?

Potential side effects aren't specified but may include reactions typical of new supplements such as digestive discomfort, allergic reactions, or changes in energy levels. Close monitoring will help identify any unexpected effects.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ change in epigenetic age from baseline to 12 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~change in epigenetic age from baseline to 12 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and change in epigenetic age from baseline to 12 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.

Primary study objectives

Biological age

Secondary study objectives

C-reactive protein

Inflammatory marker IL-6

Awards & Highlights

No Placebo-Only Group

All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups

Experimental Treatment

Group I: SRW Cel systemExperimental Treatment1 Intervention

Cel1, Cel2, Cel3 Patients will take all three supplements once daily. Patients will take 2 capsules of each supplement in the morning with food.

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Research Highlights

Information in this section is not a recommendation. We encourage patients to speak with their healthcare team when evaluating any treatment decision.

Mechanism Of Action

Side Effect Profile

Prior Approvals

Other Research

Common treatments for aging target the nine hallmarks of aging: genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. These treatments work by enhancing DNA repair, protecting telomeres, modifying epigenetic markers, improving protein homeostasis, regulating metabolic pathways, boosting mitochondrial function, clearing senescent cells, supporting stem cell function, and improving cell signaling. Addressing these hallmarks is crucial for aging patients as it can improve healthspan and reduce the incidence of age-related diseases.

Senotherapy: growing old and staying young?