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Calcium Channel Blocker

Topical diltiazem + lidocaine for Anal Fissure

Phase 2 & 3
Waitlist Available
Research Sponsored by University of Calgary
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 weeks
Awards & highlights

Summary

This trial is testing two creams, Diltiazem and Nifedipine, on patients with long-lasting anal tears. These creams help by relaxing the muscles around the tear, allowing better blood flow and faster healing.

Eligible Conditions
  • Anal Fissure
  • Rectal Disease
  • Rectal Bleeding

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Anal bleeding
Perianal irritation
Perianal pain

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Topical diltiazem + lidocaineExperimental Treatment1 Intervention
Group II: Topical nifedipine + lidocaineActive Control1 Intervention

Find a Location

Who is running the clinical trial?

University of CalgaryLead Sponsor
805 Previous Clinical Trials
883,602 Total Patients Enrolled
~101 spots leftby Sep 2025
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