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ALY688 Ophthalmic Solution for Dry Eye Syndrome (OASIS-1 Trial)

Phase 2 & 3
Waitlist Available
Research Sponsored by Allysta Pharmaceutical
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks

Summary

This trial is testing ALY688 eye drops in two strengths (0.4% and 1%) to see if they are safe and effective for people with dry eye disease.

Eligible Conditions
  • Dry Eye Syndrome

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Corneal fluorescein staining

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: ALY688 Ophthalmic Solution Concentration 2Experimental Treatment1 Intervention
Group II: ALY688 Ophthalmic Solution Concentration 1Experimental Treatment1 Intervention
Group III: Vehicle Ophthalmic SolutionPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ALY688 Ophthalmic Solution
2021
Completed Phase 3
~930

Find a Location

Who is running the clinical trial?

Allysta PharmaceuticalLead Sponsor
3 Previous Clinical Trials
233 Total Patients Enrolled
~205 spots leftby Nov 2025
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