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Gastrografin for Small Bowel Obstruction

Phase 2 & 3
Waitlist Available
Research Sponsored by Lawson Health Research Institute
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be younger than 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through study completion, up to 6 months
Awards & highlights

Study Summary

This trial is testing whether adding Gastrografin to standard non-surgical management of small bowel obstruction is effective.

Eligible Conditions
  • Small Bowel Obstruction

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through study completion, up to 6 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and through study completion, up to 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
rate of surgical intervention
Secondary outcome measures
Length of hospital stay
Rate of complications
Time to first feed
+1 more

Trial Design

2Treatment groups
Experimental Treatment
Group I: Gastrografin ArmExperimental Treatment1 Intervention
Patients will receive a single dose of undiluted Gastrografin via the nasogastric tube at 24 hours after admission for small bowel obstruction. The dose of Gastrografin will be proportional to the patient's weight and age and will be based off of the recommendations from the drug manufacturer. Dosages will range from 30 ml for infants to children less than 5 years old and 60 ml for children 5-18 years and will not be diluted.
Group II: Control ArmExperimental Treatment1 Intervention
Patients will receive a single dose of saline solution via the nasogastric tube at 24 hours after admission for small bowel obstruction. The volume of saline solution will be proportional to the volume of Gastrografin patients of similar weight and age would receive.

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Who is running the clinical trial?

Lawson Health Research InstituteLead Sponsor
664 Previous Clinical Trials
414,078 Total Patients Enrolled
~0 spots leftby Jun 2025
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