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Anti-tumor antibiotic

Abraxane dose escalation + fixed dose DOXIL for Breast Cancer

Phase 1 & 2
Waitlist Available
Led By Jame Abraham, MD
Research Sponsored by West Virginia University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
All Individual Drugs Already Approved
Approved for 10 Other Conditions
No Placebo-Only Group

Summary

Dose Finding and Efficacy Evaluation of DOXIL (Doxorubicin HCL Liposome Injection) in Combination with Abraxane (Abraxane) in Patients with Metastatic Breast Cancer (MBC) \[Phase I and II\]

Eligible Conditions
  • Breast Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Awards & Highlights

All Individual Drugs Already Approved
Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
Approved for 10 Other Conditions
This treatment demonstrated efficacy for 10 other conditions.
No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Abraxane dose escalation + fixed dose DOXILExperimental Treatment2 Interventions
Limited dose-escalation study of Abraxane and fixed dose of DOXIL in order to identify correct dose and side effect profile of the combination.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Doxorubicin
FDA approved
Paclitaxel
FDA approved

Find a Location

Who is running the clinical trial?

West Virginia UniversityLead Sponsor
184 Previous Clinical Trials
64,471 Total Patients Enrolled
4 Trials studying Breast Cancer
69 Patients Enrolled for Breast Cancer
Ortho Biotech, Inc.Industry Sponsor
32 Previous Clinical Trials
2,513 Total Patients Enrolled
1 Trials studying Breast Cancer
102 Patients Enrolled for Breast Cancer
Jame Abraham, MDPrincipal InvestigatorWest Virginia University
~0 spots leftby Nov 2025
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