Fisetin for Carpal Tunnel Syndrome

Recruiting in Palo Alto (17 mi)

Overseen byPeter C Amadio

Age: 18+

Sex: Any

Travel: May Be Covered

Time Reimbursement: Varies

Trial Phase: Phase 2

Waitlist Available

Sponsor: Peter C. Amadio, M.D.

No Placebo Group

Prior Safety Data

Trial Summary

What is the purpose of this trial?This trial is testing Fisetin, a supplement, to see if it can help people with mild to moderate carpal tunnel syndrome. The study will involve 40 participants who show signs of aging cells in their blood. Fisetin aims to reduce these aging cells and inflammation, potentially improving CTS symptoms.

Eligibility Criteria

Adults aged 21-80 with mild or moderate carpal tunnel syndrome can join this study. Women must not be pregnant, breastfeeding, or planning to become pregnant and should use birth control. Participants shouldn't have certain health conditions like severe liver disease, uncontrolled diabetes, recent wrist treatments, or be taking specific medications.

Inclusion Criteria

I am a woman who can have children and have tested negative for pregnancy.

I will not donate eggs from the start of the study until 60 days after.

Classic or probable carpal tunnel syndrome on Katz-Stirrat hand diagram

+8 more

Exclusion Criteria

My kidney function is severely impaired.

My blood counts are outside the normal range, indicating possible poor nutrition.

I have a condition like nerve disease, kidney failure, liver disease, uncontrolled diabetes, or another metabolic disorder.

+19 more

Participant Groups

The trial is testing the safety and effectiveness of Fisetin for treating carpal tunnel syndrome. It aims to see if Fisetin can relieve numbness or tingling in fingers due to CTS by comparing symptoms before and after treatment.

1Treatment groups

Experimental Treatment

Group I: Carpal Tunnel SyndromeExperimental Treatment1 Intervention

Adult men and women who have a clinical diagnosis for Carpal Tunnel Syndrome (CTS) will receive Fisetin for 2 day periods for 2 months