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Diagnostic Test
MRE + 2PD MRI for Liver Cancer
Phase 1 & 2
Waitlist Available
Led By Haesun Choi, MD
Research Sponsored by M.D. Anderson Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Timeline
Screening 3 weeks
Treatment Varies
Follow Up baseline to end of trial, up to 2 years
Awards & highlights
Summary
The goal of this clinical research study is to test the accuracy of magnetic resonance elastogram (MRE) and 2-point dixon magnetic resonance imaging (2PD MRI) using new computer software (called "phase correction algorithm") in patients who might have liver disease.
Eligible Conditions
- Liver Cancer
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ baseline to end of trial, up to 2 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~baseline to end of trial, up to 2 years
Treatment Details
Study Objectives
Study objectives can provide a clearer picture of what you can expect from a treatment.Secondary study objectives
Association Between Degrees of Stiffness Measured by MRE in kPa and Histopathological Grades of Fibrosis and Steatohepatitis
Hepatic Steatosis
Trial Design
1Treatment groups
Experimental Treatment
Group I: MRE + 2PD MRIExperimental Treatment2 Interventions
MRE - Pneumatic driver will be placed over the upper abdomen. Patient will feel a vibration (like a cell phone or beeper vibrating). This vibration will create very small waves in the body. The scanner will then receive the vibrations from the liver and use them to create images of the liver tissue. 2PD MRI - Imaging performed after the MRE procedure and lasting 20-60 seconds. This procedure is useful in identifying fat tissue.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Magnetic Resonance Elastogram
2007
Completed Phase 2
~50
2-Point Dixon Magnetic Resonance Imaging
2007
Completed Phase 2
~50
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Who is running the clinical trial?
M.D. Anderson Cancer CenterLead Sponsor
3,045 Previous Clinical Trials
1,800,040 Total Patients Enrolled
21 Trials studying Liver Cancer
9,354 Patients Enrolled for Liver Cancer
Haesun Choi, MDPrincipal InvestigatorM.D. Anderson Cancer Center
4 Previous Clinical Trials
118 Total Patients Enrolled
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