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Histone Deacetylase Inhibitor

HBI-8000 + Pembrolizumab for Non-Small Cell Lung Cancer (HBI-8000 Trial)

Phase 2
Waitlist Available
Research Sponsored by HUYABIO International, LLC.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 38 months
Awards & highlights
No Placebo-Only Group

Summary

This trial tests a combination of two drugs, HBI-8000 and pembrolizumab, for patients with advanced lung cancer. The treatment aims to make cancer cells more vulnerable and boost the immune system to fight the cancer.

Eligible Conditions
  • Non-Small Cell Lung Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~38 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 38 months for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Objective response rate (ORR)
Secondary study objectives
Disease Control Rate (DCR)
Duration of response (DoR)
Progression-Free Survival (PFS)
+1 more

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: HBI-8000 in combination with pembrolizumabExperimental Treatment1 Intervention

Find a Location

Who is running the clinical trial?

HUYABIO International, LLC.Lead Sponsor
11 Previous Clinical Trials
959 Total Patients Enrolled

Media Library

HBI-8000 (Tucidinostat) (Histone Deacetylase Inhibitor) Clinical Trial Eligibility Overview. Trial Name: NCT05141357 — Phase 2
Non-Small Cell Lung Cancer Research Study Groups: HBI-8000 in combination with pembrolizumab
Non-Small Cell Lung Cancer Clinical Trial 2023: HBI-8000 (Tucidinostat) Highlights & Side Effects. Trial Name: NCT05141357 — Phase 2
HBI-8000 (Tucidinostat) (Histone Deacetylase Inhibitor) 2023 Treatment Timeline for Medical Study. Trial Name: NCT05141357 — Phase 2
~1 spots leftby Dec 2025