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Monoclonal Antibodies

Nivatrotamab for Small Cell Lung Cancer

Phase 1 & 2
Waitlist Available
Research Sponsored by Y-mAbs Therapeutics
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from first dose until 30 days after last imp, up to 26 weeks. actual duration for treated patients were from 21 to 58 days.
Awards & highlights
No Placebo-Only Group

Summary

This trial tests nivatrotamab, a drug that helps the immune system attack small-cell lung cancer. It targets specific proteins on cancer and immune cells to help the body fight the cancer. The study aims to find the safest dose and see how well it works in patients.

Eligible Conditions
  • Small Cell Lung Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from first dose until 30 days after last imp, up to 26 weeks. actual duration for treated patients were from 21 to 58 days.
This trial's timeline: 3 weeks for screening, Varies for treatment, and from first dose until 30 days after last imp, up to 26 weeks. actual duration for treated patients were from 21 to 58 days. for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Dose Limiting Toxicities (DLTs) Phase I
Number of Participants With Adverse Events (AEs) for Different Doses of Nivatrotamab in Phase I

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: NivatrotamabExperimental Treatment1 Intervention
Subcutaneous administration of nivatrotamab up to 13 cycles

Find a Location

Who is running the clinical trial?

Y-mAbs TherapeuticsLead Sponsor
25 Previous Clinical Trials
1,554 Total Patients Enrolled
~1 spots leftby Dec 2025
Unbiased ResultsWe believe in providing patients with all the options.
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