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Local Anesthetic

"The Efficacy of Exparel Versus a Multidrug Cocktail in Soft Tissue Tumors"

Phase 2
Waitlist Available
Research Sponsored by Morristown Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 14 days
Awards & highlights
No Placebo-Only Group

Summary

This trial aims to find the best pain relief method for patients after soft tissue tumor surgery. It compares Exparel, which releases pain medication gradually, with a mix of other drugs. The goal is to see which method better controls pain and reduces the need for stronger painkillers.

Eligible Conditions
  • Soft Tissue Mass
  • Musculoskeletal Disorder
  • Musculoskeletal Disorders

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~14 days
This trial's timeline: 3 weeks for screening, Varies for treatment, and 14 days for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Pain Outcomes
Secondary study objectives
Medication Consumption

Side effects data

From 2020 Phase 3 trial • 60 Patients • NCT03270514
7%
Respiratory Failure
7%
Respiratory Insufficiency
3%
Pneumothorax
3%
Seizure
3%
Pulmonary Insufficiency
3%
Cardiac Arrest
100%
80%
60%
40%
20%
0%
Study treatment Arm
Exparel Injectable Product
Bupivacaine Hydrochloride

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

2Treatment groups
Experimental Treatment
Group I: Multi-Drug Cocktail GroupExperimental Treatment1 Intervention
70 subjects will receive a Multi-drug Cocktail
Group II: Exparel GroupExperimental Treatment1 Intervention
70 subjects will receive Exparel
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Exparel Injectable Product
2017
Completed Phase 4
~220

Find a Location

Who is running the clinical trial?

Morristown Medical CenterLead Sponsor
2 Previous Clinical Trials
675 Total Patients Enrolled
~28 spots leftby Jan 2026
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